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IPR038635 is a CCR4-NOT complex subunit 2/3/5, C-terminal domain superfamily.
<p>The Ccr4-Not complex controls mRNA metabolism at multiple levels in eukaryotic cells [[cite:PUB00088275], [cite:PUB00088276], [cite:PUB00010587]]. This complex is a major cytoplasmic deadenylase consisting of a combination of at least nine subunits, four of which have deadenylase activity [[cite:PUB00088277]]. The conserved core of the CCR4-NOT complex consists of two major modules: a catalytic module comprising two deadenylases (CAF1 or its paralogue POP2, and CCR4a or its paralogue CCR4b) and the NOT module, which minimally consists of NOT1, NOT2 and NOT3 [[cite:PUB00088316]].</p> <p>This entry represents the C-terminal domain of NOT2, NOT3 and NOT5 (subunits 2, 3 and 5 of the complex). The C-terminal regions of NOT2 and NOT3 contain a conserved SH3-like NOT-box domain which mediates NOT-module assembly [[cite:PUB00088315]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | CCR4-NOT transcription complex subunit 3; TAIR: AT5G18230.1 transcription regulator NOT2/NOT3/NOT5 family protein; Swiss-Prot: sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3; TrEMBL-Plants: tr|I1ML37|I1ML37_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0640200 | 13 | ||
| – | CCR4-NOT transcription complex subunit 3; TAIR: AT5G18230.1 transcription regulator NOT2/NOT3/NOT5 family protein; Swiss-Prot: sp|O75175|CNOT3_HUMAN CCR4-NOT transcription complex subunit 3; TrEMBL-Plants: tr|I1ML37|I1ML37_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0640200 | 13 | ||
| – | CCR4-NOT transcription complex subunit 2; TAIR: AT1G07705.2 NOT2 / NOT3 / NOT5 family; Swiss-Prot: sp|Q52JK6|VIP2_NICBE Probable NOT transcription complex subunit VIP2; TrEMBL-Plants: tr|K7LPS4|K7LPS4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0366900 | 8 | ||
| – | CCR4-NOT transcription complex subunit 2; TAIR: AT1G07705.2 NOT2 / NOT3 / NOT5 family; Swiss-Prot: sp|Q52JK6|VIP2_NICBE Probable NOT transcription complex subunit VIP2; TrEMBL-Plants: tr|I1LK90|I1LK90_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0366900 | 8 | ||
| – | CCR4-NOT transcription complex subunit 2; TAIR: AT1G07705.2 NOT2 / NOT3 / NOT5 family; Swiss-Prot: sp|Q52JK6|VIP2_NICBE Probable NOT transcription complex subunit VIP2; TrEMBL-Plants: tr|A0A0B2RMT6|A0A0B2RMT6_GLYSO Putative NOT transcription complex subunit VIP2; Found in the gene: LotjaGi3g1v0278400 | 8 | ||
| – | CCR4-NOT transcription complex subunit 2; TAIR: AT1G07705.2 NOT2 / NOT3 / NOT5 family; Swiss-Prot: sp|Q52JK6|VIP2_NICBE Probable NOT transcription complex subunit VIP2; TrEMBL-Plants: tr|A0A0B2RMT6|A0A0B2RMT6_GLYSO Putative NOT transcription complex subunit VIP2; Found in the gene: LotjaGi3g1v0278400 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |