Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR039739 is a RING-finger protein MAG2/RNF10.
<p>This entry represents a group of E3 ubiquitin-protein ligases including MAG2 from budding yeasts and RNF10 from animals, which contain a RING-finger. RNF10 has been shown to be involved in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells [[cite:PUB00090037]]. It catalyses monoubiquitination of 40S ribosomal proteins RPS2/us5 and RPS3/us3 in response to ribosome stalling [[cite:PUB00151148], [cite:PUB00151149]].</p> <p>MAG2 is E3 ubiquitin-protein ligase involved in the degradation of non-functional 18S rRNAs in response to stalled ribosomes [[cite:PUB00151147]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | RING finger protein; TAIR: AT3G26730.1 RING/U-box superfamily protein; Swiss-Prot: sp|Q32NQ8|RNF10_XENLA RING finger protein 10; TrEMBL-Plants: tr|K7MXM8|K7MXM8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0632700 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 100.00 |