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IPR039740 is a CCR4-NOT transcription complex subunit 10.
<p>CNOT10 is part of the CCR4-NOT complex, a major cellular mRNA deadenylase linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. CNOT10 is essential for the integrity of the CCR4-NOT complex and for degradation of many mRNAs [[cite:PUB00090038]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | CCR4-NOT complex | The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, including repression and activation of mRNA initiation, control of mRNA elongation, and the deadenylation and subsequent degradation of mRNA. In Saccharomyces the CCR4-NOT complex comprises a core complex of 9 proteins (Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p), Caf4p, Caf16p, and several less well characterized proteins. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | CCR4-NOT transcription complex subunit 10; TAIR: AT5G35430.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q08CL8|CNO10_DANRE CCR4-NOT transcription complex subunit 10; TrEMBL-Plants: tr|A0A0L9TRF8|A0A0L9TRF8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0275400 | 11 | ||
| – | CCR4-NOT transcription complex subunit 10; TAIR: AT5G35430.1 Tetratricopeptide repeat (TPR)-like superfamily protein; Swiss-Prot: sp|Q08CL8|CNO10_DANRE CCR4-NOT transcription complex subunit 10; TrEMBL-Plants: tr|V7CDT0|V7CDT0_PHAVU Uncharacterized protein; Found in the gene: LotjaGi4g1v0275400 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF48452 | SUPERFAMILY | 1 | 50.00 |