Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR039903

Source: InterPro

Description

IPR039903 is a E3 ubiquitin-protein ligase Zswim2.

<p>Zswim2, also known as MEX, is an E3 ubiquitin ligase that promotes death receptor-induced apoptosis [[cite:PUB00035845]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0061630
Molecular function Ubiquitin protein ligase activity Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi1g1v0406000.1
– RING/U-box superfamily protein; TAIR: AT5G11620.1 SWIM zinc finger family protein / mitogen-activated protein kinase kinase kinase (MAPKKK)-like protein; Swiss-Prot: sp|Q62925|M3K1_RAT Mitogen-activated protein kinase kinase kinase 1; TrEMBL-Plants: tr|G7J3G2|G7J3G2_MEDTR SWIM zinc finger protein/MAP kinase kinase kinase (Mapkkk), putative; Found in the gene: LotjaGi1g1v0406000
Domains
14

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00