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IPR040038

Source: InterPro

Description

IPR040038 is a TIPIN/Csm3/Swi3.

<p>Proteins in this family contain a domain found in yeast chromosome segregation in meiosis protein 3. Proteins include: <ul> <li>Chromosome segregation in meiosis protein 3, which is required for required for chromosome segregation during meiosis and DNA damage repair, forming a fork protection complex with TOF1 [[cite:PUB00062843], [cite:PUB00090446]].</li> <li>TIMELESS-interacting protein (also known as TIPIN), which is a nuclear protein that associates with the replicative helicase, and is required for efficient cell cycle arrest in response to DNA damage. It forms a checkpoint complex with TIMELESS [[cite:PUB00077532]].</li> <li>Protein TIPIN homolog, which is the orthologue of TIPIN from Caenorhabditis elegans and Drosophila melanogaster.</li> <li>Swi1-interacting protein swi3, from Schizosaccharomyces pombe, which forms a fork protection complex with swi1 [[cite:PUB00016387]].</li> </ul>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0000076
Biological process DNA replication checkpoint A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0529800.1
– Gag polyprotein; TAIR: AT3G02820.1 zinc knuckle (CCHC-type) family protein; Swiss-Prot: sp|Q6DBR4|TIPIN_DANRE TIMELESS-interacting protein; TrEMBL-Plants: tr|A0A0L9V851|A0A0L9V851_PHAAN Uncharacterized protein; Found in the gene: LotjaGi3g1v0529800
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00