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IPR040749 is a BRCC36, C-terminal helical domain.
<p>This is the C-terminal domain of BRCC36, a Zn2+ dependent deubiquitinating enzyme, present in Camponotus floridanus. BRCC36 hydrolyzes lysine linked ubiquitin chains as part of macromolecular complexes that participate in either interferon signalling or DNA-damage recognition. The domain consists of 2 non canonical helices. The domain interacts hydrophobically with helices alpha 4 and alpha 5 of KIAA0157 in the form of a coiled coil helical bundle. This interaction helps establish the association of BRCC36 with KIAA0157, a pseudo-DUB MPN-protein that is essential for the activity of BRCC36 [[cite:PUB00087097]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | Lys-63-specific deubiquitinase BRCC36; TAIR: AT1G80210.1 Mov34/MPN/PAD-1 family protein; Swiss-Prot: sp|Q4VA72|BRCC3_XENTR Lys-63-specific deubiquitinase BRCC36; TrEMBL-Plants: tr|C6T923|C6T923_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0011600 | 15 | ||
– | Lys-63-specific deubiquitinase BRCC36; TAIR: AT1G80210.1 Mov34/MPN/PAD-1 family protein; Swiss-Prot: sp|A5PJP6|BRCC3_BOVIN Lys-63-specific deubiquitinase BRCC36; TrEMBL-Plants: tr|C6T923|C6T923_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0011600 | 12 | ||
– | Lys-63-specific deubiquitinase BRCC36; TAIR: AT1G80210.1 Mov34/MPN/PAD-1 family protein; Swiss-Prot: sp|Q4VA72|BRCC3_XENTR Lys-63-specific deubiquitinase BRCC36; TrEMBL-Plants: tr|C6T923|C6T923_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0011600 | 15 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 33.33 |