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| Field | Value |
|---|---|
| Gene ID | LotjaGi3g1v0011600 |
| Transcript ID | LotjaGi3g1v0011600.1 |
| Related isoforms 2 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Lys-63-specific deubiquitinase BRCC36; TAIR: AT1G80210.1 Mov34/MPN/PAD-1 family protein; Swiss-Prot: sp|Q4VA72|BRCC3_XENTR Lys-63-specific deubiquitinase BRCC36; TrEMBL-Plants: tr|C6T923|C6T923_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi3g1v0011600 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr3:1273634..1280000) extracted from Lotus japonicus Gifu genome v1.2.
GTAGTTTTAAGAAATTATTTTCATAAAAAAATTGAAAGATCTAATATAAAATTTGAAGAGATTAATTTGGTGCAAAAATG TTAAAGATTAATTTTTTCAATATATGTGACTAGGTTTTTGTCGGAATTGAATAGAAGAAGAAAATGCAGGTGAGGTGAAT AATAGGTTTCAGGTAGAAGAAGAGAGATTCATGCAGTAACTTATGTTCTTGTTTCTGATGAACCAAAAACCGAGACAAAC CACAAAGACAATAAACAAGGTTTCGATCGGTTTGTGTTCTGTTCTTGAAGGGAAAGGGTTTGTTTGAACGAGGGTTTGTG GAGACAAAGAAAAATGTCTCTGACAAGTGTGAAAATGTCGGAAGAAGTTTGGTTAACCTGCGTCACTCATGCATTGTCCA CCGAAACCGAAGAGATTATGGGTCTTCTTCTCGGTGACATCCAGGTTTGTTCTTTTGATTTTCCCTAATTTCTTTGCTAC TATTGATGGATGTTTTTTTATGAATGATTATTGATTATTGATTGGAATTGAATTGGATGCAGCATTCGAAAAATGGGAGT GTGACTGCATTGATATGGGGTGCATCTCCTCAGACAAGGTCTGATCGCAGAAAGGATCGAGTTGAAACTAACCCTGAACA GTTGGCTGCTGCTTCTGCCCTAGCTGATATATCCTTTTTCTTCTTCTTTTTGTAAATTATCATTTTGATTCTGCTCAAAA ATATTGGGTCGGTTTCAAAATTCAATTTTGAGTAATAGTCTTTTTCATAAAATTAAGGACTAAATTAATAGTAACGAAAG CGGTAATTTTCATGTTTGGGGCATTGTTTTGGAAGGACTGAAATGATGGACCACTCCATCTTCTTATTATTATTGTTAGC TATGTGTGTATAGATCTAACTAGGTTGCTCATTTCAAAATGGTTGCTTTTGTTATGCCATTAACTTCGTAGCACAGAATG ACCGCGACCACGGGAAGAACAACGAGGGTCATTGGTTGGTACCATTCCCATCCGCATATTACAGTTCTGCCTTCGCATGT TGGTATGTTTTCGGTAACCCCCTTTTTCTCTCTCTTTACCTATCTGTTTTTGTTTGTCCTGTTGAAGTCAGGCACTTGAA TTGGAGTTGCCTGTAGTTTTTGTTTTCATTAAAACATCATTCGATGTTTCCGTTTGTGTTAAGTCGGTCATACTTTGGAG TTATGGTGTATTACCCGGGGTTGTTAATGGCTGATAGCGTAGCGTAGCGGTAAGCCCAGAAAACACTATTTCAAGCGCTA TTGCGGCACTATAGCGGGAAATAGCGGTGAATAATGGAGTAGCAGTGAACCCCCAGTGCGCTAGTGCTATTGCGCCGCTA TAGCGAGCTATTAACAAGCCCGGTGTTACCATTTGTTAAATGGAAGGTGCAAGTATGGTTTTATATGTAGTAATTTATAG CTAAGAGAGGAAATTGTTGGTGTGACGTGACTACGGGAAAAGAGGAAGTTTGTAACTATTATTAATTATTGGGATATTAT GGTGACTGGGAGACCCTTGATGTATTGCTTCAGTTTCTAGCTGTTGAAGTCAACAATGTTTACATGTTTAATATTTGAAA AGAAGGCATGTGTGATGTGTGTGATTATATGAATCAAAGATGTTGCTAGAGAGGATCAGCTGATGCAAATATTATTTCCC ATGAGAAATTCTATGGGAAGACTAAGTATGTTTTTCAATACTAGTGTATTTATTCATTGAAATGGACAGTACCTGTGAAT GTGACCGAATGATGATACTTATACAGTTACGCATTGTTACATTTATATCTCCTCACAGTCCTCTCCACAAACCACTGATA ATACCTAGGGCACCACTCTAACTTTTTTTCGGAATGGTTCAACTTGAGTGCGTGCCTCATATAGTATGTGCAACTGTCGA TTTCCTTATATCTGCTATCCTTCAATTTTCTTTTTGCTGCTTCGGAAAATTGCTATCATTCACTTTTTGTGAGTAAGGTA GGATATTATAACATTTACTGATGTCAGACACCTCAAATGTATTGGGGCTTGATTGTTGAGTTTCAATCATGTCACATTTG TTAGAAGAATAATATCAAACCATGAACATGTCTTTATTCAAAAGCTTAAGCTTTTTGAATAGTTTATTCATGAAGGCTTA ATTGCAACTTTGGTCCCCGACGTTTACCAATGCCACGATTTTGGTCCCCCACCTAATTTAATTACATGGATGGTCCCCGA CGTTGTAGGCCGTGTGCAACGTTAGTCCTACCGTTTATTTCTTAATGGAGGAGGCTTACGTGTACGTCCATTTGGAGAGA GAAATGAGGTATGAGGAGAAAGAGAAGCACGTGAGTATCACGTGACCCTTATCTGAACCCATTATACCCAAACCCCTGAC CTCCCTGGAACGAAGAAGGTAACGCGATTTAGATCCCTAGGGTTTCAAATTTGGGGATAATGAGTTCATATAAGGTTCAC GTGATACTCACGTGCTCCCCTCTCTCCTCAAATCTCCTTTTTCTCTCCAACTAGACGTCCACGTAAGCCTCCTCCATTAA GAAATAAACGGTAGGACTAATGTTGCACGCAGCCTACAACGTCGGGGACCATCCATGTAATTAAATTAGGTGGGGGACCA AAATCGTAGCATTGGTAAACATCGGGGACCAAAGTTGTAATTAAGCCATTCATGAAATATTAAATCGTAATTTTTAGCTG GAAATTTAGGTTGCAAATAATTTTTTAAATGATGGCATGTCTTTTCTAAATCAATTTTCCCTGCCTATGATTTTCACCAG TCTTCTTGTTTTGTACTTGCTTTTGTATTCCTTCTCATGTTGCTTCTTTCTTATCTTAATGTCAGCTTTTTTCTTTTTCT ATTTCTGCCAGTTTTGTTTAATTCAGAACAACAACATACAATAAGTGTACTTACTATTTTGTAGATGTGCGGACTCAGGG AATGTATCAACTTCTTGATTCTGGGTTTATCGGGTTGATTTTTTCCTGTTACAGTGAAGATGCAAACAAGGTTTTTCTTG ATTGAATGATCATTGTGTAAAACCATGTGTTCTGTATTCCTGTCAAATTTGACCTGAAATAGCTTTGGTCTGTATTCAGG TCGGAAGAATTCAAGTAATTGCTTTCCAGTCATCTGATGGGAAGCAGAATCACATGTCAAGACCTATACCTCTGTCCCCT GTAAATAGAAGCGCTGTTATTGACATAGATTCGTCACCGAGTTCCTCAGAGAATGTATCGAGAAGATCTGGTTACTTCAA GGCAGAGAGCCCGGATCAGGACACTGGTGATTCAAGAAGTGCTGGTGCTAGTAAAGTATACTTTATCGTAAATCAAATAG ATTTAACATCTGTTATGTTGCATTATGTGATTGAAGAATAGGCAATATTTTGAAAATGAAAAATGTAGAATACAGTTAGA TGCAGAATTACAGAACATGATGCAGCTTATAGAATATGTGGGACCAGGAAGTTTCTTTGTTAAAGTACAATTCTTTTATT TTCTACTTTTCTGTATTAATTTTAAACAAGCCTCTTGGATGTCGCTGCTGACAGTTTTTTAATGTGAAATTATTCATGTT AAAATACTTATATGATCATATGGCGGATATGAATTTTTCAACATGACTGTATGTCTTTTTTCAGCATCCAAATGTTTGTA TTTTTTAGTGTCCACTGTCCAGTGATAGTGAGTTCATATCATGGTGAAGTCAAGTTACTTGAACCAACTAGCTTTAGAAT CTCATGTTCTTTTCTCCATTAAAAAGCAGAAGTAGGATATAACACCCTTGCCTGGTTCCAATTTGCATTTTTTTAGGGAA GTTCTACGTAGAGACCAGGGGATTCTTTCTGATTACACTGGCTTTTGCATACAATTTTTTGTGATACGGTGAGGGGTGGG TGTAAGCTGAAATACTTAGGTTCATCTTATGGAGATGAATTCAGTCTCTTAATAATGTCCTACCAATAAAATTTTACTTG CATGTTTTTTTGTACAGGATGAATTACTTCCTCTTACGATTTTTTTTTTTAATAATTCATGTAATTATAAATTTTTGCTA GGGTGGAGGGAGATCTTCAGACTTGGGGAATTTCTTCGCTAATGCTGATGCCAGCTATCTAGGGGGAGAAAAGGGTGGAG GAAACTACCTTCTCAACAATTCGGACAGCAAAGAAATTGATATTGATCCCATGGATATGTCAGAAAGTATGCAGGAAGCT ATGCATCGTTCAAATTTGGACATGAGGTATGGAATATAGATGAGCATGTAATTGACCGCTTTGTATATTTGTTTATCAAC TGATAATTTAGGCCTATTTTTAGGATTTCGATCCCATCATGTCTCCTTGCAACATAAGGGAACATGGTGGCTGTTTTTCT AAATCTCAAGTGACTAGATAATAAAGGTCTCCATAACTGCAAGATAAACGGAAATAATTGAGGAAGAATAAGGGAAGAGA CATTTTTTATTGTAAACTAGGTTTGAATCCTACTAGGGGAGATTTTATTGTAAACATTTTTACCTTTGGATATCTGAACC TTTCCTTAGCACATATGCACCAAGCCAACAAGTGTGTATGACATGTCTTTAACATGGTACACCAAAATTTTTATATGAAG AAATATATGCAGGAGAAGGAGATGGAGATAGACATTCTGTAGAGGTTTCTCCAATATGCTTGTTAGTTAGACTTTGAATG ATAAATCAATGTCATAACTATAGATCAACTGTTTAAATATATGAAATGATATCACATTTTTCATTCTTCATTATATCATG TTTGGTCAATATAGTTTCTCAATCTTCGGTTTGAAAATAACTTTGATTTGATGGCAGTGGTGCAGAGTATGTAAGAAGAG AAATTCCCCTTTATGTTTTACCTTCCTTATCTCTTATCAACCTTGATTCACCACTAGCATCATATATGGATCTGCAACAT GTAATATTTGAAGAGGAGCGGACTGCATATAATCAAGCCATATCGCAAAATATGAGGTGATTATTTGATAAACTATCTGC TTATTCTGAATACATTTTGTTCATTTCAATGCTTATTCCATTCGTTTGTACTTTGCAGGGATGAGAAAGTGCATCCACTC ACTTTCATACACCATACTTCAACTTATCAGGCTTCATTATGCAAGTTGATTGAATATTGGTCAGAGCAAAATGTTTATTT GTTTTATTCCTCCACTTTTTATTGCTATCATTTTGTTCAATAAACAATTACTATTTTATGATACAGTTTAAGTCCTGCAA TTACTGCACTTCAAGATCGACTGAGAGAGAATGAAGTTCGGGTAATATATCAATTTATTTAATTTTATTCTTAATATATA ATCCTGGACCATATGTTAGTTTCCATTTTACCTAATCATATACTTTTTTTTACTATGATTCAATCAACTACCCAATTGGG ATTTAGAAGTTACTTGTTCACATATACTATTCAACATTAGTTCAATAGCTTTAACTATTTATTGACTTATTGCACATGTG GTTGTTGATATTGTAGTTAGCAATTATGAGTGAAGAAGCCAAGAGTCTAGAGGCTGAAGCTTATAGAGGGAGTGAAGCAA GTTTAAGTTCTCCCCGTCGAGTTGCATCACCTGTACATCAAGTTGCATCTCCTGTTCATCGGGGAAGTTTGTCTCCTGCT TCGAGGAATGTAGCTAGTCCTGGTAGCCGAAGCAGAAGAGGGTATTAAGCAATATAAATGATGATGATTTTGCTAAAATG GAATGTTTAATTCATCTTGATGTTGTAATGTTGTTGCCTCGGCAATGTGTGCTACCATGAAAATGGGGCTATAATGAAGT ATTTTGCTAGTGGGTCTATGGGTGCAAGTACGAGCATATAGGTACTTAGAGAGTTAGAGGGTACTGGCTGGGGCAAGCGT TCAAGTTACTATCTATTGGGTATGGTGGCAGGTTCATGTATTTTTATTTTTATTTTGATAATTAGGAGGGCCAACGACCC AAAACTACAAACTACACTACTCTAGTCATTGTCATTGTCATTCCTAATGCATGTATGGGGACAAATACTATAGTACCCTA ACTCAACCCTAGTAATTGTCATTCCTAATGCAGGTAGAGGAAGAAGAAAAAGGGACAAGGAAAATGGAAGCAATGAGAAA ACTTACATGAGAGATGAAATAATACTTGTAGAAGGAGATAACTCGAACTAAGACATGAGGAAGGGAAGTCGCTCCACCCA CCCACAATGGGGTGCGACTGAAATTCTTTCTGCTCTGCTAGTGTGATGGTTGTTCACACAAGTTCTTGCCTAATTTAAAA GTTCAAATCTACATAAAAAAATGTCAAATTTGTGGCAACTCAATAAA
CDS sequence (LotjaGi3g1v0011600.1) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGTCTCTGACAAGTGTGAAAATGTCGGAAGAAGTTTGGTTAACCTGCGTCACTCATGCATTGTCCACCGAAACCGAAGA GATTATGGGTCTTCTTCTCGGTGACATCCAGCATTCGAAAAATGGGAGTGTGACTGCATTGATATGGGGTGCATCTCCTC AGACAAGGTCTGATCGCAGAAAGGATCGAGTTGAAACTAACCCTGAACAGTTGGCTGCTGCTTCTGCCCTAGCTGATAGA ATGACCGCGACCACGGGAAGAACAACGAGGGTCATTGGTTGGTACCATTCCCATCCGCATATTACAGTTCTGCCTTCGCA TGTTGATGTGCGGACTCAGGGAATGTATCAACTTCTTGATTCTGGGTTTATCGGGTTGATTTTTTCCTGTTACAGTGAAG ATGCAAACAAGGTCGGAAGAATTCAAGTAATTGCTTTCCAGTCATCTGATGGGAAGCAGAATCACATGTCAAGACCTATA CCTCTGTCCCCTGTAAATAGAAGCGCTGTTATTGACATAGATTCGTCACCGAGTTCCTCAGAGAATGTATCGAGAAGATC TGGTTACTTCAAGGCAGAGAGCCCGGATCAGGACACTGGTGATTCAAGAAGTGCTGGTGCTAGTAAAGGTGGAGGGAGAT CTTCAGACTTGGGGAATTTCTTCGCTAATGCTGATGCCAGCTATCTAGGGGGAGAAAAGGGTGGAGGAAACTACCTTCTC AACAATTCGGACAGCAAAGAAATTGATATTGATCCCATGGATATGTCAGAAAGTATGCAGGAAGCTATGCATCGTTCAAA TTTGGACATGAGTGGTGCAGAGTATGTAAGAAGAGAAATTCCCCTTTATGTTTTACCTTCCTTATCTCTTATCAACCTTG ATTCACCACTAGCATCATATATGGATCTGCAACATGTAATATTTGAAGAGGAGCGGACTGCATATAATCAAGCCATATCG CAAAATATGAGGGATGAGAAAGTGCATCCACTCACTTTCATACACCATACTTCAACTTATCAGGCTTCATTATGCAAGTT GATTGAATATTGTTTAAGTCCTGCAATTACTGCACTTCAAGATCGACTGAGAGAGAATGAAGTTCGGTTAGCAATTATGA GTGAAGAAGCCAAGAGTCTAGAGGCTGAAGCTTATAGAGGGAGTGAAGCAAGTTTAAGTTCTCCCCGTCGAGTTGCATCA CCTGTACATCAAGTTGCATCTCCTGTTCATCGGGGAAGTTTGTCTCCTGCTTCGAGGAATGTAGCTAGTCCTGGTAGCCG AAGCAGAAGAGGGTATTAA
Protein sequence (LotjaGi3g1v0011600.1) extracted from Lotus japonicus Gifu v1.2 Proteins.
MSLTSVKMSEEVWLTCVTHALSTETEEIMGLLLGDIQHSKNGSVTALIWGASPQTRSDRRKDRVETNPEQLAAASALADR MTATTGRTTRVIGWYHSHPHITVLPSHVDVRTQGMYQLLDSGFIGLIFSCYSEDANKVGRIQVIAFQSSDGKQNHMSRPI PLSPVNRSAVIDIDSSPSSSENVSRRSGYFKAESPDQDTGDSRSAGASKGGGRSSDLGNFFANADASYLGGEKGGGNYLL NNSDSKEIDIDPMDMSESMQEAMHRSNLDMSGAEYVRREIPLYVLPSLSLINLDSPLASYMDLQHVIFEEERTAYNQAIS QNMRDEKVHPLTFIHHTSTYQASLCKLIEYCLSPAITALQDRLRENEVRLAIMSEEAKSLEAEAYRGSEASLSSPRRVAS PVHQVASPVHRGSLSPASRNVASPGSRSRRGY
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| Gene3D | 1 | 163 | 163 | 6.0E-52 | – | |
| PANTHER | 3 | 386 | 384 | 1.6E-128 | – | |
| PANTHER | 3 | 386 | 384 | 1.6E-128 | – | |
| CDD | 3 | 367 | 365 | 3.53559E-104 | ||
| Pfam | 3 | 120 | 118 | 3.0E-24 | ||
| SUPERFAMILY | 5 | 134 | 130 | 1.15E-15 | – | |
| SMART | 5 | 151 | 147 | 1.2E-16 | ||
| ProSiteProfiles | 6 | 152 | 147 | 22.071 | ||
| MobiDBLite | 172 | 212 | 41 | - | – | |
| MobiDBLite | 172 | 187 | 16 | - | – | |
| Pfam | 297 | 380 | 84 | 4.5E-23 | ||
| Coils | 356 | 383 | 28 | - | – | |
| MobiDBLite | 389 | 432 | 44 | - | – | |
| MobiDBLite | 411 | 425 | 15 | - | – |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Thiol-dependent ubiquitin-specific protease activity | Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein. | ||
| Molecular function | Protein binding | Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). | ||
| Biological process | DNA repair | The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway. | ||
| Cellular component | BRCA1-A complex | A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites. | ||
| Biological process | Protein K63-linked deubiquitination | A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein. | ||
| Cellular component | BRISC complex | A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains. |
Expression pattern of LotjaGi3g1v0011600.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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