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IPR041221 is a Anaphase-promoting complex subunit 1, C-terminal.
<p>This is the C-terminal domain of anaphase-promoting complex subunit 1 (APC1)[[cite:PUB00091489]].</p> <p>Apc1 is the largest of the subunits of the anaphase-promoting complex or cyclosome. The anaphase-promoting complex is a multiprotein subunit E3 ubiquitin ligase complex that controls segregation of chromosomes and exit from mitosis in eukaryotes [[cite:PUB00091489], [cite:PUB00057287], [cite:PUB00055977], [cite:PUB00098994]]. Infection of human fibroblasts with human cytomegalovirus (HCMV) leads to cell cycle dysregulation, which is associated with the inactivation of the anaphase-promoting complex [[cite:PUB00057288]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Anaphase-promoting complex subunit 1; TAIR: AT5G05560.2 E3 ubiquitin ligase; Swiss-Prot: sp|Q9FFF9|APC1_ARATH Anaphase-promoting complex subunit 1; TrEMBL-Plants: tr|G7K258|G7K258_MEDTR Anaphase-promoting complex subunit 1; Found in the gene: LotjaGi1g1v0076600 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 100.00 |