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IPR041370

Source: InterPro

Description

IPR041370 is a Methyltransferase EEF1AKMT1/ZCCHC4.

<p>This is a protein of approximately 200 residues which is conserved from plants to humans [[cite:PUB00001857]]. It contains a highly conserved QFW motif close to the N terminus and a DPPF motif in the centre. The DPPF motif is characteristic of N-6 adenine-specific DNA methylases, and this family is found in eukaryotes [[cite:PUB00054136]]. Proteins in this entry include EEF1A lysine methyltransferase 1 (EEF1AKMT1) and ZCCHC4. EEF1AKMT1 is a protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-79' [[cite:PUB00085186]]. ZCCHC4 is an rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA [[cite:PUB00092431]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0008168
Molecular function Methyltransferase activity Catalysis of the transfer of a methyl group to an acceptor molecule.
Subterm of

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
LotjaGi5g1v0112000.1
– Protein-lysine N-methyltransferase; TAIR: AT3G58470.1 nucleic acid binding / methyltransferase; Swiss-Prot: sp|Q9CY45|N6MT2_MOUSE Protein-lysine N-methyltransferase N6amt2; TrEMBL-Plants: tr|A0A0R0IGD8|A0A0R0IGD8_SOYBN Protein-lysine N-methyltransferase GLYMA_09G103300; Found in the gene: LotjaGi5g1v0112000
Domains
10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 100.00