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IPR041729

Description

IPR041729 is a Formyltetrahydrofolate deformylase, C-terminal hydrolase domain.

<p>Formyl-FH4 Hydrolase catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to FH4 and formate. Formate is the substrate of phosphoribosylglycinamide transformylase for step three of de novo purine nucleotide synthesis. Formyl-FH4 hydrolase has been proposed to regulate the balance of FH4 and C1-FH4 in the cell. The enzyme uses methionine and glycine to sense the pools of C1-FH4 and FH4, respectively [[cite:PUB00007025]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 1

Transcript Name Description Predicted domains Domain count
Methionyl-tRNA formyltransferase; TAIR: AT5G47435.1 formyltetrahydrofolate deformylase; Swiss-Prot: sp|Q93YQ3|PURU1_ARATH Formyltetrahydrofolate deformylase 1, mitochondrial; TrEMBL-Plants: tr|A0A0L9TQX6|A0A0L9TQX6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi4g1v0202000 17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd08648 CDD 1 100.00