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IPR042216

Source: InterPro

Description

IPR042216 is a MitoNEET, CDGSH iron-sulfur domain.

<p>CDGSH iron-sulfur domains (CISDs) are classified into seven major types and are widely distributed throughout the three domains of life [[cite:PUB00056986]]. This superfamily represents the C-terminal domain found in the human CISD protein mitoNEET, also designated CSD1, an iron-containing integral protein of the outer mitochondrial membrane (OMM). MitoNEET contains two domains: a β-cap region and a cluster-binding domain, containing the CDGSH motif, that coordinates two acid-labile 2Fe-2S clusters (one bound to each protomer) [[cite:PUB00042908]]. The CDGSH iron-sulphur domain is oriented towards the cytoplasm and is tethered to the mitochondrial membrane by a more N-terminal domain found in higher vertebrates [[cite:PUB00044559], [cite:PUB00042908]]. The whole protein regulates oxidative capacity and might be involved in electron transfer.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
LotjaGi2g1v0158700.1
– CDGSH iron-sulfur domain-containing protein 2; TAIR: AT5G51720.1 2 iron, 2 sulfur cluster binding protein; Swiss-Prot: sp|Q9FLI7|NEET_ARATH CDGSH iron-sulfur domain-containing protein NEET; TrEMBL-Plants: tr|I3T106|I3T106_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0158700
Domains
7
LotjaGi2g1v0158700.2
– CDGSH iron-sulfur domain-containing protein 2; TAIR: AT5G51720.1 2 iron, 2 sulfur cluster binding protein; Swiss-Prot: sp|Q9FLI7|NEET_ARATH CDGSH iron-sulfur domain-containing protein NEET; TrEMBL-Plants: tr|I3T106|I3T106_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0158700
Domains
7

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SM00704 SMART 1 50.00