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GO:0006283

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Transcription-coupled nucleotide-excision repair
Full defintion The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
Subterm of

Relationships

The relationship of GO:0006283 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
PMID
How nucleotide excision repair protects against cancer.Friedberg EC
Nat Rev Cancer. 2001 Oct; 1 (1): 22–33.PMID: 11900249

Eukaryotic cells can repair many types of DNA damage. Among the known DNA repair processes in humans, one type--nucleotide excision repair (NER)--specifically protects against mutations caused indirectly by environmental carcinogens. Humans with a hereditary defect in NER suffer from xeroderma pigmentosum and have a marked predisposition to skin cancer caused by sunlight exposure. How does NER protect against skin cancer and possibly other types of environmentally induced cancer in humans?

Associated Lotus transcripts 1

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
LotjaGi1g1v0360500.1
– WD40 repeat-like protein; TAIR: AT1G27840.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q13216|ERCC8_HUMAN DNA excision repair protein ERCC-8; TrEMBL-Plants: tr|I1K866|I1K866_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0360500
GO terms
1

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0006283
Biological process Transcription-coupled nucleotide-excision repair 1 100.00