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GO:0008352

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description Katanin complex
Full defintion A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).
Subterm of

Relationships

The relationship of GO:0008352 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0008352, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
PMID
Cellular Samurai: katanin and the severing of microtubules.Quarmby L
J Cell Sci. 2000 Aug; 113 ( Pt 16) (): 2821–7.PMID: 10910766

Recent biochemical studies of the AAA ATPase, katanin, provide a foundation for understanding how microtubules might be severed along their length. These in vitro studies are complemented by a series of recent reports of direct in vivo observation of microtubule breakage, which indicate that the in vitro phenomenon of catalysed microtubule severing is likely to be physiological. There is also new evidence that microtubule severing by katanin is important for the production of non-centrosomal microtubules in cells such as neurons and epithelial cells. Although it has been difficult to establish the role of katanin in mitosis, new genetic evidence indicates that a katanin-like protein, MEI-1, plays an essential role in meiosis in C. elegans. Finally, new proteins involved in the severing of axonemal microtubules have been discovered in the deflagellation system of Chlamydomonas.

Associated Lotus transcripts 7

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj2g3v0915090.1
– PREDICTED: katanin p80 WD40 repeat-containing subunit B1 homolog 1-like [Glycine max] gi|356573375|ref|XP_003554837.1|
GO terms
3
Lj6g3v2066940.1
– Katanin p80 WD40-containing subunit B1 [Medicago truncatula] gi|357446405|ref|XP_003593480.1|
GO terms
3
LotjaGi2g1v0236500.1
– Katanin p80 WD40 repeat-containing subunit B1 homolog; TAIR: AT5G08390.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q8H0T9|KTNB1_ARATH Katanin p80 WD40 repeat-containing subunit B1 homolog; TrEMBL-Plants: tr|K7MVR8|K7MVR8_SOYBN Katanin p80 WD40 repeat-containing subunit B1 homolog; Found in the gene: LotjaGi2g1v0236500
GO terms
3
LotjaGi2g1v0236500.2
– Katanin p80 WD40 repeat-containing subunit B1 homolog; TAIR: AT5G08390.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q8H0T9|KTNB1_ARATH Katanin p80 WD40 repeat-containing subunit B1 homolog; TrEMBL-Plants: tr|K7MVR8|K7MVR8_SOYBN Katanin p80 WD40 repeat-containing subunit B1 homolog; Found in the gene: LotjaGi2g1v0236500
GO terms
3
LotjaGi2g1v0236500.3
– Katanin p80 WD40 repeat-containing subunit B1 homolog; TAIR: AT5G23430.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q8H0T9|KTNB1_ARATH Katanin p80 WD40 repeat-containing subunit B1 homolog; TrEMBL-Plants: tr|K7MVR8|K7MVR8_SOYBN Katanin p80 WD40 repeat-containing subunit B1 homolog; Found in the gene: LotjaGi2g1v0236500
GO terms
3
LotjaGi2g1v0236500.4
– Katanin p80 WD40 repeat-containing subunit B1 homolog; TAIR: AT5G08390.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q8H0T9|KTNB1_ARATH Katanin p80 WD40 repeat-containing subunit B1 homolog; TrEMBL-Plants: tr|K7MVR8|K7MVR8_SOYBN Katanin p80 WD40 repeat-containing subunit B1 homolog; Found in the gene: LotjaGi2g1v0236500
GO terms
3
LotjaGi6g1v0336900.1
– Katanin p80 WD40 repeat-containing subunit B1 homolog; TAIR: AT1G61210.1 Transducin/WD40 repeat-like superfamily protein; Swiss-Prot: sp|Q8H0T9|KTNB1_ARATH Katanin p80 WD40 repeat-containing subunit B1 homolog; TrEMBL-Plants: tr|G7ILH1|G7ILH1_MEDTR Katanin p80 WD40 repeat-containing subunit B1 homolog; Found in the gene: LotjaGi6g1v0336900
GO terms
3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0051013
Biological process Microtubule severing 1 14.29