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GO:0042720

View this GO term in other databases

Overview

Field Value
Namespace Cellular component
Short description Mitochondrial inner membrane peptidase complex
Full defintion Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
Subterm of

Relationships

The relationship of GO:0042720 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of n.a.
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0042720, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
PMID
Mitochondrial processing peptidases.Gakh O, Cavadini P, Isaya G
Biochim Biophys Acta. 2002 Sep 2; 1592 (1): 63–77.PMID: 12191769

Three peptidases are responsible for the proteolytic processing of both nuclearly and mitochondrially encoded precursor polypeptides targeted to the various subcompartments of the mitochondria. Mitochondrial processing peptidase (MPP) cleaves the vast majority of mitochondrial proteins, while inner membrane peptidase (IMP) and mitochondrial intermediate peptidase (MIP) process specific subsets of precursor polypeptides. All three enzymes are structurally and functionally conserved across species, and their human homologues begin to be recognized as potential players in mitochondrial disease.

Associated Lotus transcripts 1

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
LotjaGi1g1v0440100.2
– Mitochondrial inner membrane protease subunit 2; TAIR: AT3G08980.1 Peptidase S24/S26A/S26B/S26C family protein; Swiss-Prot: sp|Q6AZD4|IMP2L_DANRE Mitochondrial inner membrane protease subunit 2; TrEMBL-Plants: tr|I3SVG3|I3SVG3_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0440100
GO terms
4

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0042720
Cellular component Mitochondrial inner membrane peptidase complex 1 100.00