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GO:0051315

View this GO term in other databases

Overview

Field Value
Namespace Biological process
Short description Attachment of mitotic spindle microtubules to kinetochore
Full defintion The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
Subterm of

Relationships

The relationship of GO:0051315 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0051315, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCtb
PMID
A Centromere-Signaling Network Underlies the Coordination among Mitotic Events.Trivedi P, Stukenberg PT
Trends Biochem Sci. 2016 Feb; 41 (2): 160–174.PMID: 26705896

There is increasing evidence that regulators of the spindle checkpoint, kinetochore-microtubule attachments, and sister chromatid cohesion are part of an interconnected mitotic regulatory circuit with two positive feedback loops and the chromosome passenger complex (CPC) at its center. If true, this conceptual breakthrough needs to be integrated into models of mitosis. In this review, we describe this circuit and point out how the double feedback loops could provide insights into the self-organization of some mitotic processes and the autonomy of every chromosome on the mitotic spindle. We also provide working models for how mitotic events may be coordinated by this circuit.

Associated Lotus transcripts 2

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
Lj0g3v0355069.1
– PREDICTED: kinetochore protein NDC80 homolog [Glycine max] gi|356557509|ref|XP_003547058.1|
GO terms
2
LotjaGi6g1v0357700.1
– Kinetochore NDC80-like protein; TAIR: AT3G54630.1 kinetochore protein; Swiss-Prot: sp|O14777|NDC80_HUMAN Kinetochore protein NDC80 homolog; TrEMBL-Plants: tr|I1MDQ7|I1MDQ7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0357700
GO terms
2

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
GO:0051315
Biological process Attachment of mitotic spindle microtubules to kinetochore 1 50.00