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| Field | Value |
|---|---|
| Gene ID | LotjaGi6g1v0177500 |
| Transcript ID | LotjaGi6g1v0177500.1 |
| Related isoforms 1 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | 2-isopropylmalate synthase; TAIR: AT2G26800.1 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A151T0C4|A0A151T0C4_CAJCA Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Found in the gene: LotjaGi6g1v0177500 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr6:46928334..46935255) extracted from Lotus japonicus Gifu genome v1.2.
ACCAAACCAAGTTTCAACTTTTTATTTAATAAACAACCAACTAACTCTTCCTCACGCTACCTTTCTCACCTTCTTCTTCT CCTTCTTCTTCCTCATACTCTGTTCTTTCGTAAATATACCAAATCCAATTTCCCCCAATTTCTAGGGTTTCGTTGAAACC CTAACTACCTCTTGCATTCCCGCCAAAATTACCTTCTCATTTTGATTTCTTTCAGGTCTGTCTTCTTTTCCCAATTCTCA ATTTTCCTGTATTTTTGCTGAACAGAATGATCCCAAAAAATTAAAAAATCAATGATTGGCTATGGTTGATTGATTGCTTT TAATTATGAGTTCTGGATTGTGTGTTCATTCATTCAATTCAATTTTCTTTCTTTCTTACAATTAAGTTCAAGTGTCCAAC CTTAAGCTGATTTTTCATGTTGTTGCTGGTTGATTATGTGGTTATTGCTCACTTGGGAGTAAATTGTGGATGTGGTTATA TGAGGAGTTGAATTGTAGTCTTTGTTTGACATGTTAAACCAAAGGATCTTAATTACAATTTCAAGGTGTAACAATGGTAA CTTAAGAATCTGACTCACTGTATAATGTGGTTTAATGGTCTCAAGTAGACAATGCTTAGGGTTTATTGAATTTTTTCTTA AAAGTTAGTTCGATACTTCGATTTAACTCTTGCATTTGCTTTGCACATGATAATGCTTATTGGGGAGCTTAAGAACTCTG ACTTAGCTGAGGTTATAGGTTTAAAGAAATTTCTGTTTCAAACTTTCAGCTGTGTTCCTCATTTCTGAATTTAAGGATTT TTATTTTTTTTTCTGTCTCTGAGGGTACAGTGACATTGGCTGTTAACTTGTAAATGTTTGATGGTTTGATAAACTTCTTT TTTCTTGTTTAGATTTTCCTTTTTTTTTAAAAGAGTTTGGATACGTATTTTTGTAGATGGAACTTGTTTTCATATATTTG AGTGTACATGATTCACTTGTAAAGCAAGCAACAATTATGAATAGTTCAGAGATATATAATTCTTATGCACATGAGGCCCT ATATCTTGAAACATTAGACGTTGTGACTTTGAGTCGATGGCCATGGTTAAAGTCTTGAAAGGGAGAAATGTCTTGAACAG ACAAAGGATCAAGTCCAGTGACTTGAAAGATATGAGTATCAGTTTCATTTGCAGATACCTTTGTGACTTGGGCTATCCTT ATTTGAGTAAACAAAGATTAGGAGGCAGAGATTTTGGGATGAAAATCACTTCACGTTTGCTTGTTACAACAAAAATATGT GGAAGCAGAAAGTGGTGGGCAACTTATAGCCCATCCTATTGAAGAAAAATTAGTTCAAGAAGATTTTCCATCCTGCCTAG CAACACGGAATTAAAATCAAAATCCTTTATGTTTGACTCCATTTTCTCTCCCCTCCTCATTTTCCACCTCTCAAATATGT ATAACCTAAACCAAAGCCAGCTGAATGTGTTGCTGTTTTCTTTATTAACCTATTGAATTTTGCTTAAATCCCAGTTATTT AACTATCTTTTACATCATCAGTAGTTAGTGAAATCTATAAAGGCAAAATTTATCTTGCAATTTTAGCTTATACCACCTGC TTATGCATCAAGTAGTAAACCAGAAGTATTACTTGTCAATATATTTCACTGTATGAAGATGCATAGAGTAGTCACATGAT GTGCTGATGAAAAGATTATAGTGAAAAATGATAGAAAGAATTTTAAATAAATTCCAGATGCACAGTACTTATTCTCAACA TCTTTTACCAGTTTCCTTTTACCCATCGACTTCACTATGTCAAGCTTGGAGGAGCCACTTGGCCTTGACAAGTTGCCAAG CATGAGTACCATAGATAGAATCCAGAGGTTCTCATCTGGTGCTTGCTGCCGTCCCAGTGTAGATAATTTGGGTATGGGAA ACTGCTTTATTGATGGAAGAAGCTGCAGTACATCTAACAGCTGCAAGTGAGTTGATTTTCCAATTTATTGCAAGTTGACA CTTCTGCATTTATTTATTTTTCATTGAACTTCTTTTTGTCCTACTTTACATTGCATTGGCTTCTGTCACATGTTTTTTAA TCAATTATCTCCCACATCTATAACTAACCTTAAGGCTATCTTTCATGCAGTGAAGATAATGAAGAGTACACAGCAGAGAC ATTCCCTTGGAAAAGGCAAACCAGGAACGGGTCTAGAGGTGATTCTTCAAGTCAAAAGACTATGACCATCAGGAGGAACT CAATGAAATCTGGAATGATTGATAATTCATTGCACACCCCTGGTTACCAGTATAGTCCAAAGCACAATAACAAAGAAACA CAAGATATGGCATATAAGGTAACGTAATGACTGCATTACTTTCTTTTCACAATTTTTTTTCACAGCTTTTAAATTAGTTA TTCACGTGGTGCATCTTTTTGTGTCTCCAAAGTTTTTATATTACAAATTTTAAGCTTTCTCTTGTTGGTTGATTTCATCA TATTTCTTTGGCCTGTAAGTCACATTTAAAATTTTTATTTGGGCAATGCAGTTTATGAATGGTATGCCAAAGTTTGTAAA GATAGTTGAAGTTGGTCCAAGGGATGGCTTACAAAATGAGAAGAACATTGTACCGACATCTGTAAAGATTGAATTGATTC ATAGACTAGCATCTTCTGGTTTATCTGTTATTGAGGCTACTAGTTTTGTATCTCCCAAGTGGGTCCCACAGGTATTATGG CTTTACCATATTCATTTAGTTGATATTGATATTATGAATGATTGACATGTTAAACTTTCTTCAAGGAATATTTACATGAT ATTAGTTATCAATTCCCTTAAAAAAAAGTTAAATGTCATTTTCTGTTCTATAAACTGAACTAGTTGATTTTCTTCAAAAT AATTCCCCTGCTTTCTATTTGTGCTTGAGACAAATGAATATTTATATTTTCACCCTTTTCTTTTCGTCCAAATTAATTCC CCACAAAACCACTCATTCTAAACGACCCTACCCACTTGGTGCACAGTTTTAGTCTACCTGTCCATTTTTTAAGATTTGAT GACAACTACAGTTGTTATCCTTTCTTAATCTTAACCAACTTGTTTCCTGTGTGATTTGAGATTTACCTGCTTGAATTTCA TTCTATCTCTTTATGTTTCAGTTGGCTGATGCAAAGGATGTAATGCAAGCAGTTAAAAACCTGGGAGGCATCAGATTGCC AGTTCTGACCCCTAATTTAAAGGTGCAAATGTCTAAAAAAACTATAAATGTTGCAGATTTTACATTCAGATATCTCATAT GTTTCATTTATAGGGTTTTGAAGCTGCTATAGCTGCTGGTGCTAGAGAAATAGCTGTTTTTGCAGCAGCCTCTGAATCTT TCTCAAAATCAAACATCAATTGTAGTATTGAAGAGAGCCTTGCTCGCTATCGAGCTGTCACAAGTGCTGCTAAAGAGCTC TCAATTCCTGTTCGAGGGTATGTCTTTTGTTTTTTCCTTCATTATTCTAAGCATCCATGAAATACTCTTCACTTCAGTAT ATTTGCAAGTTTGCGTTTAAGCCAGACTGGAAATTCCAATAGATTTTGATTTCGATATTTTGTACAGGATTTCCCTGCAA TTTCTCCTTTGTTTTAGGGTAGAACCTGTAAATTAATTGAACAAGTTATCTTCAATTGATGGATTTTCTACATGTTCTGT TCTGGGGAAGCAATATTTTTGTATTGTAACGGTTTTTTTCATTGTGAAACCTAGCTGAACTTATTTACTTATATATTGCT GACTCTAATCTGTACTTGAAGCATGGATTACACATAATCATCATTTTATCATTTTCTGAAGTTTCAATTTCATCATTAAG AATGACTGCAGTGATTGAGTGCAACTTTAAGCTAAGAGTAGACCTAGAAATGGTTTTATATCTTCAACAGTTACCATAGT TGAGATCCCTGGTCCTTATCAGTCAATTAAAAAGTATGTAATCAGCTTTTTATACCCTTCTCCATTGTATTTTATTACTT TTCAAACCAGTGCAAGAACCGATACAGATGTTCAACCATGGGAAGTTTAAAAAGAGAAATTTTAATTATATACATTTTAA CTTAAACATTTCAAATATGATAAACCTATTGACTAAAGTATTACCAATACGTATAAAACAATCAATAATATTTATGAAAT TTTCTTTATGCCATACATTAAATAGTTTTTACAATTTATAGAAAGATATATTGTTAGCTGAAAAAGCAGTTTTTTTTGTA ACGATTAGAAGTCAACTAATAGAAACAACATAGTTTAATCAAAGGTGAAAAAAATGTTATAAGCTGTTCTTGCATACTAT TCACTCAATTATTTAGTTTTTGTTTATTCTTGTTCCCCGTCTTTCTTAAGTCTTAACAATTGAATGCCAAACAAAATCTA AAATTTGTTCAATATTAAATACTCTGTATAAGTGATAAGTTATCTATTTTATTAGAAGACTTCGTAAAACTTATATTTTA TTTACAAGGGTAGGGAAACTGGAGAGTTATACTCAGTTACTTACACTCATGTGCACACATTGTTGGAGACGTGCACGAGG ACTAGAGATGTTGTATAATTTTATTGATTTGAGGGAAAATTTTCTTGCTTCACTGTGATTGGTGATGATGTTGCGATTGG AACATTTTTTTTCCTTCCTAACCTTTATTCCCATTGCTGTACCATTTGATCCTAGATTACACGAAATATTTTTCAATATC AGTCTAAAGATCTATATTTGTATTGTTTTATTTTTTTTTTTACTTTTTTTAGACAGTTACTTTAAACTAAGTTAATTTTT AGTATCAGTGAAGACTCTTCATGGTATTGTTTGTAAGGAAACCAGGTCAAGCCGTCAAGGTCTGACTGTTAGACAAGTGA AAGTGCCAGACATTGTAAATTTTAGGAAAGAGAAATTCGGCTTCCCTTGATCTCTTCTGCTTATCAGTTCTCTTTATTGA AATTTCATAGGTATGTATCATGTGTCGCTGGATGCCCAGTGGAAGGACCAGTCCCTCCTTCACAAGTGGCTTATGTGGCT AAAGAATTATATGATATGGGTTGCTTTGAAATCTCCCTTGGTGACACAATTGGAGTCGGCACACCAGGTAATGAGTTAGA TGACATTATATTTTATAAAAAATAAGGGCAGATTTGGTTTGAGAAAACATTAATTTGTTTTTATTTCTTATTTTCACTAA TAGTTATAAAAATGTCGCTTTATTTTACAAATTTCTGCTTTCAAATATTTGTATAAAAATGGTGAAAACAACATATATTT TATTTTCTCCTTTTCCTGTACAAGTATTTGAAAGTAGAAAACAAAGTGAAAATAAGGTAGTATTTTTTTAATTATCATTG AAAATTGGAAATCAAAACTGAAAACATTTTCTCAAATCAAATAGGCCCTCAGCTATCCATGTTTGATCCAACACTGATCT AGTGAAGTACTGTCCTTTTGTGATATAGACAAGTTGCTCTATTCTTGTGTAGGTTTTTCCAAATGCAAGCATGATAATTT AGGGTTCTTTATTCTTCAGTGCTCCTTTGTTTTTTTATTCTAATTAACCAACTTCAAATGTAAGGAAGATTCAAATCTTG GTTGATAATCTACAAGAATTTGCTTTAAAGATATTCGTCCACTTTTGTAGTATAGCGCTCGGCAATATCTCATAATTGTT TGACATATTTTCTTAATTTTCATCACCACATCTTTCGCTGAACCTCATATTTGACTGCTGATATTTGTCCCCATTTGTTT CCTAATGCTTTACAGCAAAGCATTAAGTGTCAAATCTTGGAAATATTGGGGGATAAATGTCAAACTTTGTTCTTTACCTC TTAACCATGAATTTCTCACTGAGAATTTGCTATTTCTGTTGTGATTAGGAACTGTAGTTCCAATGCTTTTGGCAGTAATG GCTGTTGTACCGATAGATAAACTTGCCGTCCACTTCCATGACACATACGGGCAATCCCTTCCAAATATTCTTGTGTCTCT CCAAGTAAGTCAACAAGCCACATCTTGAAGTTTTTATTTGTTTGTCCATTCATGCATACAATTTATTGAGCTTGCCTCTT TTAGACATGCAACTGAACCACCATTGTACAATTACAAGCAATGGAAATTCTTCACCATCCATGAACACCTTTTTTCGATA GAACAGGGCCTGCATTTTATCTCTTGGCTGTCACAGTTATTAATGGACATCATTAATTTGTATATGTACAGATGGGGATT AGTGCAGTGGATTCTTCAGTCTCTGGTCTAGGTGGCTGTCCATATGCTAAGGGAGCTTCAGGAAATGTAGCTACTGAAGA TGTTGTGTACATGCTGAATGGGCTTGGTGTGAAGACAAATGTTGATCTGGGAAAGCTCTTGTCAGCCGGGGACTTCATCA GCAAGCATCTGGGCCGCCCATCTGGCTCAAAGACTGCCGTCGCCTTAGGCCGAGTCACATCTGATGCTTCCAAGATATGA TAATGTATTGTACCATAAAAATATATATAAATAGGTGCTTCAAGCAATGACAGGTCATTCTATATGTATATTTCTTTTCT TTTCTTTTTTTCCTTTTTCTGCATAATTATATGAGAGGAATAAATTGCCCACTCCTGTGGATGAGTTGGGAAGAGAGATG TAATGGCTGTAATCTGCCAATAGCAATATCAATAGCAAGTGCAAGCTTCTCATTTGAATTAAAGCTTGCAATTTTTTCCT TGTTTCAGCCATCGTGCATTTGTTGTATAATGTATATCTGTTTGGCTATACGCATGACTAGTTTAACTCTTAACCTAAAC AGAACAGAGGAAATAATGTTCACACTTAACTAAACTTTATTTACCTGCATTTTGAGGGTTATGGGGAATGGCGATTAAGA AATTTTATCATTTTGCAGGGTTATCCTGTCCAACTACCATCG
CDS sequence (LotjaGi6g1v0177500.1) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGTCAAGCTTGGAGGAGCCACTTGGCCTTGACAAGTTGCCAAGCATGAGTACCATAGATAGAATCCAGAGGTTCTCATC TGGTGCTTGCTGCCGTCCCAGTGTAGATAATTTGGGTATGGGAAACTGCTTTATTGATGGAAGAAGCTGCAGTACATCTA ACAGCTGCAATGAAGATAATGAAGAGTACACAGCAGAGACATTCCCTTGGAAAAGGCAAACCAGGAACGGGTCTAGAGGT GATTCTTCAAGTCAAAAGACTATGACCATCAGGAGGAACTCAATGAAATCTGGAATGATTGATAATTCATTGCACACCCC TGGTTACCAGTATAGTCCAAAGCACAATAACAAAGAAACACAAGATATGGCATATAAGTTTATGAATGGTATGCCAAAGT TTGTAAAGATAGTTGAAGTTGGTCCAAGGGATGGCTTACAAAATGAGAAGAACATTGTACCGACATCTGTAAAGATTGAA TTGATTCATAGACTAGCATCTTCTGGTTTATCTGTTATTGAGGCTACTAGTTTTGTATCTCCCAAGTGGGTCCCACAGTT GGCTGATGCAAAGGATGTAATGCAAGCAGTTAAAAACCTGGGAGGCATCAGATTGCCAGTTCTGACCCCTAATTTAAAGG GTTTTGAAGCTGCTATAGCTGCTGGTGCTAGAGAAATAGCTGTTTTTGCAGCAGCCTCTGAATCTTTCTCAAAATCAAAC ATCAATTGTAGTATTGAAGAGAGCCTTGCTCGCTATCGAGCTGTCACAAGTGCTGCTAAAGAGCTCTCAATTCCTGTTCG AGGGTATGTATCATGTGTCGCTGGATGCCCAGTGGAAGGACCAGTCCCTCCTTCACAAGTGGCTTATGTGGCTAAAGAAT TATATGATATGGGTTGCTTTGAAATCTCCCTTGGTGACACAATTGGAGTCGGCACACCAGGAACTGTAGTTCCAATGCTT TTGGCAGTAATGGCTGTTGTACCGATAGATAAACTTGCCGTCCACTTCCATGACACATACGGGCAATCCCTTCCAAATAT TCTTGTGTCTCTCCAAATGGGGATTAGTGCAGTGGATTCTTCAGTCTCTGGTCTAGGTGGCTGTCCATATGCTAAGGGAG CTTCAGGAAATGTAGCTACTGAAGATGTTGTGTACATGCTGAATGGGCTTGGTGTGAAGACAAATGTTGATCTGGGAAAG CTCTTGTCAGCCGGGGACTTCATCAGCAAGCATCTGGGCCGCCCATCTGGCTCAAAGACTGCCGTCGCCTTAGGCCGAGT CACATCTGATGCTTCCAAGATATGA
Protein sequence (LotjaGi6g1v0177500.1) extracted from Lotus japonicus Gifu v1.2 Proteins.
MSSLEEPLGLDKLPSMSTIDRIQRFSSGACCRPSVDNLGMGNCFIDGRSCSTSNSCNEDNEEYTAETFPWKRQTRNGSRG DSSSQKTMTIRRNSMKSGMIDNSLHTPGYQYSPKHNNKETQDMAYKFMNGMPKFVKIVEVGPRDGLQNEKNIVPTSVKIE LIHRLASSGLSVIEATSFVSPKWVPQLADAKDVMQAVKNLGGIRLPVLTPNLKGFEAAIAAGAREIAVFAAASESFSKSN INCSIEESLARYRAVTSAAKELSIPVRGYVSCVAGCPVEGPVPPSQVAYVAKELYDMGCFEISLGDTIGVGTPGTVVPML LAVMAVVPIDKLAVHFHDTYGQSLPNILVSLQMGISAVDSSVSGLGGCPYAKGASGNVATEDVVYMLNGLGVKTNVDLGK LLSAGDFISKHLGRPSGSKTAVALGRVTSDASKI
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PANTHER | 1 | 434 | 434 | 1.4E-246 | – | |
| PANTHER | 1 | 434 | 434 | 1.4E-246 | ||
| MobiDBLite | 67 | 115 | 49 | - | – | |
| Gene3D | 128 | 427 | 300 | 4.2E-130 | ||
| SUPERFAMILY | 130 | 422 | 293 | 8.35E-71 | – | |
| Pfam | 135 | 408 | 274 | 9.1E-55 | ||
| ProSiteProfiles | 135 | 402 | 268 | 34.309 | ||
| CDD | 137 | 410 | 274 | 3.48081E-178 | – |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Catalytic activity | Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. | ||
| Molecular function | Hydroxymethylglutaryl-CoA lyase activity | Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA. | ||
| Cellular component | Mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | ||
| Biological process | Ketone body biosynthetic process | The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA. |
Expression pattern of LotjaGi6g1v0177500.1, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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