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GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
GO term | Namespace | Name | Definition | Relationships |
---|---|---|---|---|
Molecular function | Hydroxymethylglutaryl-CoA lyase activity | Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA. | ||
Cellular component | Mitochondrion | A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. | ||
Biological process | Ketone body biosynthetic process | The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA. |
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | 2-isopropylmalate synthase 2; TAIR: AT2G26800.5 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|I1N8Q3|I1N8Q3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0661300 | 15 | ||
– | 2-isopropylmalate synthase 2; TAIR: AT2G26800.5 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A0R0EW28|A0A0R0EW28_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0661300 | 10 | ||
– | 2-isopropylmalate synthase; TAIR: AT2G26800.1 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A151T0C4|A0A151T0C4_CAJCA Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Found in the gene: LotjaGi6g1v0177500 | 11 | ||
– | 2-isopropylmalate synthase; TAIR: AT2G26800.1 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A151T0C4|A0A151T0C4_CAJCA Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Found in the gene: LotjaGi6g1v0177500 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
mobidb-lite | MobiDBLite | 1 | 25.00 |