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IPR030020

Description

IPR030020 is a .

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Hydroxymethylglutaryl-CoA lyase activity Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.
Cellular component Mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
Biological process Ketone body biosynthetic process The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
2-isopropylmalate synthase 2; TAIR: AT2G26800.5 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|I1N8Q3|I1N8Q3_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0661300 15
2-isopropylmalate synthase 2; TAIR: AT2G26800.5 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A0R0EW28|A0A0R0EW28_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0661300 10
2-isopropylmalate synthase; TAIR: AT2G26800.1 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A151T0C4|A0A151T0C4_CAJCA Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Found in the gene: LotjaGi6g1v0177500 11
2-isopropylmalate synthase; TAIR: AT2G26800.1 Aldolase superfamily protein; Swiss-Prot: sp|O81027|HMGCL_ARATH Hydroxymethylglutaryl-CoA lyase, mitochondrial; TrEMBL-Plants: tr|A0A151T0C4|A0A151T0C4_CAJCA Putative 3-hydroxymethyl-3-methylglutaryl-CoA lyase 2; Found in the gene: LotjaGi6g1v0177500 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 25.00