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| Field | Value |
|---|---|
| Gene ID | LotjaGi3g1v0510900 |
| Transcript ID | LotjaGi3g1v0510900.3 |
| Related isoforms 3 | |
| Lotus japonicus genome version | Gifu v1.2 |
| Description | Thymidylate synthase; TAIR: AT4G34570.4 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|B0BLI5|B0BLI5_LOTJA Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi3g1v0510900 |
| Working Lj name | n.a. |
Genomic sequence (LjG1.1_chr3:92803076..92806562) extracted from Lotus japonicus Gifu genome v1.2.
ATGGCCAGTGACTCTCTTGTGATCTCCAATGGCCATGACAATGGCAATTTAGAGCTGAGTCCACAGAGGACTTACCAAGC TGTAGTGATTGCGACCCCGGACATGGGCATTTCCAAAGATGGAAAATTGCCCTGGGCATTGCCTACTGATCAAAAGTTTT TTGAGGAGATCACTACAAAAACATCTGATCCTGGGAAGAAGAATGCTGTTGTCATGGGTAGGAAATCATGGGAGGCCATC CCTCCTGAGAAAAGGCCTCTCTGTGGTCGCCTTAATGTTGTGCTGACTCGCTCGGGTAGCTTTGATATTGCAACAGCGGA GAATGTTGTTATTTGTGGAAGTGTGTCTTCTGCCATGGAACTGTTAGCTTCTTCTCCTTACAGCATGTCAATTGAGAAAG TGTTTCTTACCGGAGGTGGCGAGATTTTTAGGTATATACATTGTTTAATCTTCTTTCTTTTCCTCTATTAATCTTTCCTG TCATAAGCATATTAAGATATTTCTTCATTGTAGCTGATGATTTTAATGTACAGAGAGGCTCTTAATGCTCCTGGATGTGA AGCTGTCCATATTACAGAAATTGAAGCAAGCATCGAGTGTGACACTTTCATGCCTCGAGTTGATTTCTCTGTATTTCATC CATGGTACTCATCTTTTCCTTTGGTGGAAAACAACATCCGCTATTCTTTCAACACCTATGTGCGTGTAAGGAGTTCTGCA GAAGAATCCCTTGGTCAGAATACTGATCCAAGTTTTGATAGTGATTCAGACTCTCTAAAATTTGAGGTCAAGAAATTTTC TTTTCTTCCTAAAATGATTTTTGAGAGTCATGAGGAGTACAAGTATCTTAGGTTGGTTCAAGAAATCATTTCTGAAGGTA CAGTTAAGGATGACAGGACTGGGACTGGTACCTTGTCAAAATTTGGTTGCCAGGTAACATTTGAATTTGATTGGTTTTTT GAGGAATTGCTTTACTTTATATGCTGATTTCCTTCCCTGTAATTCCACAGATGAGGTTTAATCTCCGCAGAAGCTTTCCA CTTCTAACAACTAAGGTATATGCAAATTTTGGTTTGAGATTTGTATAATAATCGACCGTGCATAGTAATGTGTTTTCTGT ATGCTCCTATTCTTCTTATATTTTTTCATGTAGTTATTGTTTGTTGTTTTGTTTGTTACCTTGTATCGTTCTTAGGTAAG ACTGTATCTATTTTACATTTTGACATAAAAAGATAACATGACTTCTTCATTTGGTTTGTAGAAAGTATTTTGGCGAGGGG TTGTTGAAGAGCTTCTTTGGTTTATCAGTGGCTCAACGAGTGCCAAGGTAATGATATATTTTGACCATCTTTCTGCACGT ATAAATTGTTATTGATCAAAAGTATATAATATGATTGGATTCTTATGAATATACACGAGTAAATAAATTTAGTCTATCTT ATTCCCGATGTCTTACTAGTTAATACAGAATGTCAAGATATTAAAAAATAAAATATGTGCTATGTGTTTTCTAGGATCAT GAAGAGTTTGTTGAAGCTTTTCTTGGTTCTTTACTGATTTTTTTTTTAACGTTTAGTGACGTTAATACAGAATGTCAAGA TATTAAGAAAATAAAATATGTGCTATGTGTTTTCTAGGATCATGAAGAGTTTGTTGAAGCTTTTCTTGGTTCTTTACTGA TTTTTTTTTAACGTTTAGTGACGATTTAAAAGGCTGGCTTATGAAGCTCTTAACTCACAAAGATGCTCGCTCATATCTGT CACTGTATTAAAGAATTTCTAGTCTCACTAGTTTTCAAGTTGAGTAAAATTTTGACATTATATACTGATGGCTATTACAG ATGTTCATGGAGTTTATTTTGTATACTGAAAATTTAGTAGTCTCTTTGTTATTGAATATGAATGGTTTGATGATGGCATG ATAAACACCTGTTTGTCACATTGTTTCTGCATTTATTCCATAAAAATATGTGCTTCTGGACCAAAGTTCTTTTAAAGTGC TGCAGGCATGAGGTCTTTCTTTTAGGTTCACAAAGAATGTCTTATTGGTTCGTCATATACGAGTGTGGTAAATTGTATTC TGAAAACTTGTTATATACAGGTGCTGCAAGAAAAAGGCATTCATATATGGGATGGCAATGCATCCAGGGAATACCTTGAT AGGCAAGCATGAATATCAACTTATTTATATATAAATTGCAAATATTTCTTTTCCATGAAGTTATTAACCGGCTTGACCTT TTAAATTACAGCATTGGTTTGACAGAAAGGGAGGAGGGTGACTTAGGGCCTGTCTATGGGTTTCAGTGGAGGCACTTTGG CGCTAGGTAGGTGGATTGCACCTTTATCTCTGTCGGTCTTGGATTAAACTTTGTTTTATGGGATTAATTAGCTCTTTGCT TCCCTTCTTACATTTGATAGGTATACTAACATGCATGATGACTACTCCGGCAAAGGATTTGATCAGCTTTTAGATGTTAT TAACAAGATAAAGCATAATCCTGATGATCGACGGATCATTCTCTCAGCTTGGAATCCATCTGATCTTAAGTTGATGGCAC TTCCTCCTTGCCACATGTTTGCGCAGGTCTGCAGCTATATTTGAGTTTCTCTTTTAAAGGTATCCTCACCCTCCTCTCTC CTTCTCTCTAAGTTTTTCCTGCTTCCTTTTTTTTCATGCAGTTCTATGTAGCAAATGGGGAGTTGTCATGTCAAATGTAT CAGCGATCTGCGGATATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCTTGACATGCATGATTGCTCATGT TTGTGGTATGCAAATTATGCCAGCTTTTGCTAGACTTACATATTTATCCAGATGTACCTTAAGTCTTTACTTTCATGGGT TTAATAGGGATTTGTCATTTTGTCCCATTATTCCTACACCTAGTTTTTGCAATTATTTTTACACTAGTCATGTTTCTCCT TATCTCCTTTAGATCACTCATCCCATAATTCTTTCTCTTCCCTTCCTGTCTCCTATGTGTAAAAATAAAGGAAATAAAAT AAAGTAAAAATCTCTGTTAATTGAATAATTAATTGAGGACAAACTTAATATTGAAAGAAAATCAGCATCACATATTGGAC TAATCACTCCTTATTTGATGTCCTTTCCTTGCCAGACCTAGTTCCGGGTGATTTTATCCATGTTATTGGGGATGCACATG TTTACCGCAATCATGTGAAGCCTTTGCAGGAACAGCTCCAGAACCTGCCAAGACCTTTTCCGGTATGTGTTCATGTTTAA GAAAATCATCTGATTTAATGTATGCATACAAAATATTTACCTTAAGGCTCTCTTTTTAATTGTTCTTTCCTTGTTGACTA CCTTAACTTCGATCAGATTTTGAAGATAAATCCAAAGAAGAAAGATATAGATTCTTTTGAGGCTACTGATTTCAAGCTCA TAGGCTATGATCCTCACCAGAAGATCCAAATGAAGATGGCTGTTTAG
CDS sequence (LotjaGi3g1v0510900.3) extracted from Lotus japonicus Gifu v1.2 CDS.
ATGGCCAGTGACTCTCTTGTGATCTCCAATGGCCATGACAATGGCAATTTAGAGCTGAGTCCACAGAGGACTTACCAAGC TGTAGTGATTGCGACCCCGGACATGGGCATTTCCAAAGATGGAAAATTGCCCTGGGCATTGCCTACTGATCAAAAGTTTT TTGAGGAGATCACTACAAAAACATCTGATCCTGGGAAGAAGAATGCTGTTGTCATGGGTAGGAAATCATGGGAGGCCATC CCTCCTGAGAAAAGGCCTCTCTGTGGTCGCCTTAATGTTGTGCTGACTCGCTCGGGTAGCTTTGATATTGCAACAGCGGA GAATGTTGTTATTTGTGGAAGTGTGTCTTCTGCCATGGAACTGTTAGCTTCTTCTCCTTACAGCATGTCAATTGAGAAAG TGTTTCTTACCGGAGGTGGCGAGATTTTTAGAGAGGCTCTTAATGCTCCTGGATGTGAAGCTGTCCATATTACAGAAATT GAAGCAAGCATCGAGTGTGACACTTTCATGCCTCGAGTTGATTTCTCTGTATTTCATCCATGGTACTCATCTTTTCCTTT GGTGGAAAACAACATCCGCTATTCTTTCAACACCTATGTGCGTGTAAGGAGTTCTGCAGAAGAATCCCTTGGTCAGAATA CTGATCCAAGTTTTGATAGTGATTCAGACTCTCTAAAATTTGAGGTCAAGAAATTTTCTTTTCTTCCTAAAATGATTTTT GAGAGTCATGAGGAGTACAAGTATCTTAGGTTGGTTCAAGAAATCATTTCTGAAGGTACAGTTAAGGATGACAGGACTGG GACTGGTACCTTGTCAAAATTTGGTTGCCAGTTATTGTTTGTTGTTTTGTTTGTTACCTTAAAGTATTTTGGCGAGGGGT TGTTGAAGAGCTTCTTTGGTTTATCAGTGGCTCAACGAGTGCCAAGCATTGGTTTGACAGAAAGGGAGGAGGGTGACTTA GGGCCTGTCTATGGGTTTCAGTGGAGGCACTTTGGCGCTAGGTATACTAACATGCATGATGACTACTCCGGCAAAGGATT TGATCAGCTTTTAGATGTTATTAACAAGATAAAGCATAATCCTGATGATCGACGGATCATTCTCTCAGCTTGGAATCCAT CTGATCTTAAGTTGATGGCACTTCCTCCTTGCCACATGTTTGCGCAGTTCTATGTAGCAAATGGGGAGTTGTCATGTCAA ATGTATCAGCGATCTGCGGATATGGGCCTGGGCGTGCCATTTAATATTGCATCTTATGCGCTCTTGACATGCATGATTGC TCATGTTTGTGACCTAGTTCCGGGTGATTTTATCCATGTTATTGGGGATGCACATGTTTACCGCAATCATGTGAAGCCTT TGCAGGAACAGCTCCAGAACCTGCCAAGACCTTTTCCGATTTTGAAGATAAATCCAAAGAAGAAAGATATAGATTCTTTT GAGGCTACTGATTTCAAGCTCATAGGCTATGATCCTCACCAGAAGATCCAAATGAAGATGGCTGTTTAG
Protein sequence (LotjaGi3g1v0510900.3) extracted from Lotus japonicus Gifu v1.2 Proteins.
MASDSLVISNGHDNGNLELSPQRTYQAVVIATPDMGISKDGKLPWALPTDQKFFEEITTKTSDPGKKNAVVMGRKSWEAI PPEKRPLCGRLNVVLTRSGSFDIATAENVVICGSVSSAMELLASSPYSMSIEKVFLTGGGEIFREALNAPGCEAVHITEI EASIECDTFMPRVDFSVFHPWYSSFPLVENNIRYSFNTYVRVRSSAEESLGQNTDPSFDSDSDSLKFEVKKFSFLPKMIF ESHEEYKYLRLVQEIISEGTVKDDRTGTGTLSKFGCQLLFVVLFVTLKYFGEGLLKSFFGLSVAQRVPSIGLTEREEGDL GPVYGFQWRHFGARYTNMHDDYSGKGFDQLLDVINKIKHNPDDRRIILSAWNPSDLKLMALPPCHMFAQFYVANGELSCQ MYQRSADMGLGVPFNIASYALLTCMIAHVCDLVPGDFIHVIGDAHVYRNHVKPLQEQLQNLPRPFPILKINPKKKDIDSF EATDFKLIGYDPHQKIQMKMAV
Data for domain prediction are obtained with InterProScan, and merged with InterPro data obtained from the EB-eye REST service.
| Prediction algorithm | Identifier | Start | End | Length | E-value | InterPro ID |
|---|---|---|---|---|---|---|
| PIRSF | 7 | 287 | 281 | 1.8E-89 | ||
| PANTHER | 20 | 281 | 262 | 2.7E-242 | – | |
| PANTHER | 20 | 281 | 262 | 2.7E-242 | – | |
| Gene3D | 23 | 204 | 182 | 2.3E-50 | ||
| ProSiteProfiles | 24 | 201 | 178 | 41.649 | ||
| SUPERFAMILY | 26 | 201 | 176 | 1.51E-49 | ||
| CDD | 27 | 200 | 174 | 2.60954E-51 | ||
| Pfam | 27 | 201 | 175 | 2.0E-30 | ||
| SUPERFAMILY | 226 | 502 | 277 | 6.02E-106 | ||
| Gene3D | 238 | 284 | 47 | 1.8E-8 | ||
| CDD | 248 | 455 | 208 | 1.73187E-90 | ||
| Gene3D | 298 | 502 | 205 | 9.2E-97 | ||
| PANTHER | 304 | 502 | 199 | 2.7E-242 | – | |
| PANTHER | 304 | 502 | 199 | 2.7E-242 | – | |
| PIRSF | 305 | 502 | 198 | 2.3E-118 | ||
| Pfam | 315 | 502 | 188 | 2.7E-78 | ||
| TIGRFAM | 315 | 502 | 188 | 1.3E-75 | ||
| PRINTS | 353 | 372 | 20 | 1.6E-39 | ||
| ProSitePatterns | 364 | 392 | 29 | - | ||
| PRINTS | 379 | 394 | 16 | 1.6E-39 | ||
| PRINTS | 397 | 423 | 27 | 1.6E-39 | ||
| PRINTS | 435 | 452 | 18 | 1.6E-39 |
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Dihydrofolate reductase activity | Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+. | ||
| Molecular function | Thymidylate synthase activity | Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate. | ||
| Biological process | DTMP biosynthetic process | The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate). | ||
| Biological process | One-carbon metabolic process | The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states. | ||
| Biological process | Tetrahydrofolate biosynthetic process | The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group. | ||
| Biological process | Oxidation-reduction process | A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons. |
Expression pattern of LotjaGi3g1v0510900.3, powered by ExpAt. For advanced configuration, data transformation and export options, view expression data in the ExpAt application.
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