Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

PR00108

Source: PRINTS

Description

Thymidylate synthase family signature

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004799
Molecular function Thymidylate synthase activity Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
Subterm of
GO:0006231
Biological process DTMP biosynthetic process The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
Subterm of

Associated Lotus transcripts 13

Transcript Name Description Predicted domains Domain count
Lj0g3v0331489.1
– PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase-like [Glycine max] gi|356545155|ref|XP_003541010.1|
Domains
17
Lj1g3v3381400.2
– PREDICTED: bifunctional dihydrofolate reductase-thymidylate synthase-like [Cicer arietinum] gi|502130863|ref|XP_004500795.1|
Domains
24
Lj3g3v3363560.1
– CM0216.390.nc [Lotus japonicus] gi|164564740|dbj|BAF98221.1|
Domains
20
LotjaGi1g1v0565200.1
– Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K754|I1K754_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
25
LotjaGi1g1v0565200.2
– Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
25
LotjaGi1g1v0565200.3
– Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
25
LotjaGi1g1v0565200.4
– Thymidylate synthase; TAIR: AT4G34570.4 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
24
LotjaGi1g1v0565200.6
– Dihydrofolate reductase / thymidylate synthase; TAIR: AT4G34570.1 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
24
LotjaGi1g1v0565200.7
– Thymidylate synthase; TAIR: AT2G16370.1 thymidylate synthase 1; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1K753|I1K753_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
25
LotjaGi1g1v0565200.8
– Thymidylate synthase; TAIR: AT4G34570.1 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|I1LQ11|I1LQ11_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi1g1v0565200
Domains
13
LotjaGi3g1v0510900.1
– Thymidylate synthase; TAIR: AT4G34570.4 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|B0BLI5|B0BLI5_LOTJA Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi3g1v0510900
Domains
23
LotjaGi3g1v0510900.3
– Thymidylate synthase; TAIR: AT4G34570.4 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|B0BLI5|B0BLI5_LOTJA Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi3g1v0510900
Domains
22
LotjaGi3g1v0510900.4
– Thymidylate synthase; TAIR: AT4G34570.4 thymidylate synthase 2; Swiss-Prot: sp|P51820|DRTS_SOYBN Bifunctional dihydrofolate reductase-thymidylate synthase; TrEMBL-Plants: tr|B0BLI5|B0BLI5_LOTJA Bifunctional dihydrofolate reductase-thymidylate synthase; Found in the gene: LotjaGi3g1v0510900
Domains
23

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd00351 CDD 1 7.69