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IPR000566 is a Lipocalin/cytosolic fatty-acid binding domain.
<p>This entry represents the lipocalin/cytosolic fatty-acid binding domain of a group of proteins that belong to the calycin superfamily.</p> <p>Proteins which transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids share limited regions of sequence homology and a common tertiary structure architecture [[cite:PUB00001491], [cite:PUB00004787], [cite:PUB00004981], [cite:PUB00005013], [cite:PUB00005340]]. This is an eight stranded antiparallel β-barrel with a repeated + 1 topology enclosing a internal ligand binding site [[cite:PUB00005013], [cite:PUB00004981]]. The name 'lipocalin' has been proposed [[cite:PUB00001491]] for this protein family, but cytosolic fatty-acid binding proteins are also included. The sequences of most members of the family, the core or kernal lipocalins, are characterised by three short conserved stretches of residues, while others, the outlier lipocalin group, share only one or two of these [[cite:PUB00000205], [cite:PUB00005013]]. Proteins known to belong to this family include alpha-1-microglobulin (protein HC); alpha-1-acid glycoprotein (orosomucoid) [[cite:PUB00004508]]; aphrodisin; apolipoprotein D; beta-lactoglobulin; complement component C8 gamma chain [[cite:PUB00003778]]; crustacyanin [[cite:PUB00001391]]; epididymal-retinoic acid binding protein (E-RABP) [[cite:PUB00005238]]; insectacyanin; odorant-binding protein (OBP); human pregnancy-associated endometrial alpha-2 globulin; probasin (PB), a rat prostatic protein; prostaglandin D synthase ([ec:5.3.99.2]) [[cite:PUB00005379]]; purpurin; Von Ebner's gland protein (VEGP) [[cite:PUB00001451]]; and lizard epididymal secretory protein IV (LESP IV) [[cite:PUB00002777]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: outer membrane lipoprotein blc-like [Cicer arietinum] gi|502149930|ref|XP_004507714.1| | 15 | ||
| – | PREDICTED: outer membrane lipoprotein blc-like [Cicer arietinum] gi|502149930|ref|XP_004507714.1| | 15 | ||
| – | Apolipoprotein D; TAIR: AT3G47860.1 chloroplastic lipocalin; Swiss-Prot: sp|Q9STS7|CHL_ARATH Chloroplastic lipocalin; TrEMBL-Plants: tr|I3S940|I3S940_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0034700 | 11 | ||
| – | Temperature-induced lipocalin; TAIR: AT5G58070.1 temperature-induced lipocalin; Swiss-Prot: sp|Q9FGT8|TIL_ARATH Temperature-induced lipocalin-1; TrEMBL-Plants: tr|I3T3W6|I3T3W6_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0285700 | 14 | ||
| – | Temperature-induced lipocalin; TAIR: AT5G58070.1 temperature-induced lipocalin; Swiss-Prot: sp|Q9FGT8|TIL_ARATH Temperature-induced lipocalin-1; TrEMBL-Plants: tr|I3TAJ2|I3TAJ2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0205600 | 14 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |