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IPR000905 is a Gcp-like domain.
<p>This domain was identified in proteins including Kae1 and Gcp (YgjD), which were originally thought to be endopeptidases belonging to the peptidase M22 family [[cite:PUB00002152]]. However, there is a lack of experimental evidence to support peptidase activity as a general property, and this has not been confirmed in other orthologues [[cite:PUB00047751], [cite:PUB00059910]]. Recent research indicates that the Kae1 and Gcp proteins are involved in the biosynthesis of N6-threonylcarbamoyl adenosine, a universal modification found at position 37 of tRNAs that read codons beginning with adenine [[cite:PUB00059911]]. This domain is also present in Bacillus subtilis YdiC and Escherichia coli YeaZ. These proteins have been recently renamed as TsaB, and have also been shown to be involved in N6-Threonylcarbamoylad enonsine (t(6)A) biosynthesis [[cite:PUB00063366], [cite:PUB00063355]].</p>
This description is obtained from EB-eye REST.
Transcript | Name | Description | Predicted domains | Domain count |
---|---|---|---|---|
– | PREDICTED: probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep-like [Glycine max] gi|356573183|ref|XP_003554743.1| | 11 | ||
– | PREDICTED: probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep-like [Glycine max] gi|356573183|ref|XP_003554743.1| | 10 | ||
– | PREDICTED: probable tRNA threonylcarbamoyladenosine biosynthesis protein osgep-like [Glycine max] gi|356573183|ref|XP_003554743.1| | 10 | ||
– | PREDICTED: probable tRNA threonylcarbamoyladenosine biosynthesis protein osgepl1-like [Glycine max] gi|356506230|ref|XP_003521890.1| | 11 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT4G22720.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9WVS2|OSGEP_RAT Probable tRNA N6-adenosine threonylcarbamoyltransferase; TrEMBL-Plants: tr|I1NCH1|I1NCH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0788800 | 13 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT4G22720.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9WVS2|OSGEP_RAT Probable tRNA N6-adenosine threonylcarbamoyltransferase; TrEMBL-Plants: tr|I1NCH1|I1NCH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0788800 | 13 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT4G22720.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9WVS2|OSGEP_RAT Probable tRNA N6-adenosine threonylcarbamoyltransferase; TrEMBL-Plants: tr|I1NCH1|I1NCH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0788800 | 11 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT4G22720.1 Actin-like ATPase superfamily protein; Swiss-Prot: sp|Q9WVS2|OSGEP_RAT Probable tRNA N6-adenosine threonylcarbamoyltransferase; TrEMBL-Plants: tr|I1NCH1|I1NCH1_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0788800 | 13 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT2G45270.1 glycoprotease 1; Swiss-Prot: sp|O22145|OSGP2_ARATH Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A0S3SYJ9|A0A0S3SYJ9_PHAAN Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Found in the gene: LotjaGi3g1v0435500 | 12 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT2G45270.1 glycoprotease 1; Swiss-Prot: sp|O22145|OSGP2_ARATH Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A0S3SYJ9|A0A0S3SYJ9_PHAAN Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Found in the gene: LotjaGi3g1v0435500 | 19 | ||
– | TRNA N6-adenosine threonylcarbamoyltransferase; TAIR: AT2G45270.1 glycoprotease 1; Swiss-Prot: sp|O22145|OSGP2_ARATH Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; TrEMBL-Plants: tr|A0A0S3SYJ9|A0A0S3SYJ9_PHAAN Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Found in the gene: LotjaGi3g1v0435500 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
Predicted domain | Source | Observations | Saturation (%) |
---|---|---|---|
TIGR03723 | TIGRFAM | 1 | 9.09 |