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IPR001079 is a Galectin, carbohydrate recognition domain.
<p>Galectins (also known as galaptins or S-lectin) are a family of proteins defined by having at least one characteristic carbohydrate recognition domain (CRD) with an affinity for beta-galactosides and sharing certain sequence elements. Members of the galectins family are found in mammals, birds, amphibians, fish, nematodes, sponges, and some fungi. Galectins are known to carry out intra- and extracellular functions through glycoconjugate-mediated recogntion. From the cytosol they may be secreted by non-classical pathways, but they may also be targeted to the nucleus or specific sub-cytosolic sites. Within the same peptide chain some galectins have a CRD with only a few additional amino acids, whereas others have two CRDs joined by a link peptide, and one (galectin-3) has one CRD joined to a different type of domain [[cite:PUB00038165], [cite:PUB00043740]].</p> <p>The galectin carbohydrate recognition domain (CRD) is a β-sandwich of about 135 amino acid. The two sheets are slightly bent with 6 strands forming the concave side and 5 strands forming the convex side. The concave side forms a groove in which carbohydrate is bound, and which is long enough to hold about a linear tetrasaccharide [[cite:PUB00021763], [cite:PUB00026983]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Carbohydrate binding | Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: beta-1,3-galactosyltransferase 15-like [Cicer arietinum] gi|502093839|ref|XP_004490069.1| | 17 | ||
| – | PREDICTED: probable beta-1,3-galactosyltransferase 19-like [Cicer arietinum] gi|502093476|ref|XP_004489955.1| | 14 | ||
| – | PREDICTED: probable beta-1,3-galactosyltransferase 19-like [Cicer arietinum] gi|502152174|ref|XP_004508800.1| | 11 | ||
| – | PREDICTED: probable beta-1,3-galactosyltransferase 16-like isoform X1 [Cicer arietinum] gi|502150744|ref|XP_004508102.1| | 16 | ||
| – | PREDICTED: probable beta-1,3-galactosyltransferase 20-like [Glycine max] gi|356512339|ref|XP_003524877.1| | 18 | ||
| – | PREDICTED: probable beta-1,3-galactosyltransferase 20-like [Cicer arietinum] gi|502078551|ref|XP_004485982.1| | 18 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT5G62620.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9LV16|B3GTJ_ARATH Hydroxyproline O-galactosyltransferase GALT6; TrEMBL-Plants: tr|A0A0L9UBP3|A0A0L9UBP3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0186500 | 19 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT1G26810.1 galactosyltransferase1; Swiss-Prot: sp|Q8L7F9|B3GTF_ARATH Beta-1,3-galactosyltransferase GALT1; TrEMBL-Plants: tr|V7CHJ3|V7CHJ3_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0302800 | 16 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT5G62620.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9LV16|B3GTJ_ARATH Hydroxyproline O-galactosyltransferase GALT6; TrEMBL-Plants: tr|V7CKY1|V7CKY1_PHAVU Uncharacterized protein; Found in the gene: LotjaGi2g1v0310800 | 16 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT5G62620.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9LV16|B3GTJ_ARATH Hydroxyproline O-galactosyltransferase GALT6; TrEMBL-Plants: tr|K7KMM0|K7KMM0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0244000 | 15 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT3G06440.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9ASW1|B3GTG_ARATH Hydroxyproline O-galactosyltransferase GALT3; TrEMBL-Plants: tr|K7MJT7|K7MJT7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0334800 | 15 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT3G06440.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9ASW1|B3GTG_ARATH Hydroxyproline O-galactosyltransferase GALT3; TrEMBL-Plants: tr|A0A072URG8|A0A072URG8_MEDTR Beta-1,3-galactosyltransferase-like protein; Found in the gene: LotjaGi4g1v0334800 | 18 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT3G06440.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9ASW1|B3GTG_ARATH Hydroxyproline O-galactosyltransferase GALT3; TrEMBL-Plants: tr|A0A072URG8|A0A072URG8_MEDTR Beta-1,3-galactosyltransferase-like protein; Found in the gene: LotjaGi4g1v0334800 | 18 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT3G06440.1 Galactosyltransferase family protein; Swiss-Prot: sp|Q9ASW1|B3GTG_ARATH Hydroxyproline O-galactosyltransferase GALT3; TrEMBL-Plants: tr|A0A072URG8|A0A072URG8_MEDTR Beta-1,3-galactosyltransferase-like protein; Found in the gene: LotjaGi4g1v0334800 | 18 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT4G21060.2 Galactosyltransferase family protein; Swiss-Prot: sp|A7XDQ9|B3GTK_ARATH Hydroxyproline O-galactosyltransferase GALT2; TrEMBL-Plants: tr|A0A0R0K0I8|A0A0R0K0I8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0362500 | 19 | ||
| – | Beta-1,3-galactosyltransferase-like protein; TAIR: AT4G21060.2 Galactosyltransferase family protein; Swiss-Prot: sp|A7XDQ9|B3GTK_ARATH Hydroxyproline O-galactosyltransferase GALT2; TrEMBL-Plants: tr|I1MF03|I1MF03_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0312900 | 18 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 6.25 |