Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message
IPR001608 is a Alanine racemase, N-terminal.
<p>Alanine racemase plays a role in providing the D-alanine required for cell wall biosynthesis by isomerising L-alanine to D-alanine.</p> <p>The molecular structure of alanine racemase from Bacillus stearothermophilus was determined by X-ray crystallography to a resolution of 1.9 A [[cite:PUB00000440]]. The alanine racemase monomer is composed of two domains, an eight-stranded α/β barrel at the N terminus, and a C-terminal domain essentially composed of β-strands. The pyridoxal 5'-phosphate (PLP) cofactor lies in and above the mouth of the α/β barrel and is covalently linked via an aldimine linkage to a lysine residue, which is at the C terminus of the first β-strand of the α/β barrel.</p> <p>This N-terminal domain is also found in the PROSC (proline synthetase co-transcribed bacterial homologue) family of proteins, which are not known to have alanine racemase activity.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: proline synthase co-transcribed bacterial homolog protein-like isoform X1 [Cicer arietinum] gi|502166388|ref|XP_004513878.1| | 12 | ||
| – | PREDICTED: proline synthase co-transcribed bacterial homolog protein-like [Cicer arietinum] gi|502079184|ref|XP_004486181.1| | 9 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT4G26860.1 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q9Z2Y8|PROSC_MOUSE Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|A0A0S3S737|A0A0S3S737_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0156000 | 13 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT4G26860.1 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q9Z2Y8|PROSC_MOUSE Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|A0A0S3S737|A0A0S3S737_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0156000 | 13 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT1G11930.2 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q3T0G5|PROSC_BOVIN Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|I3T823|I3T823_MEDTR Proline synthetase associated protein; Found in the gene: LotjaGi6g1v0290900 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd06822 | CDD | 1 | 20.00 |