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IPR029066 is a PLP-binding barrel.
<p>This entry represents the PLP (pyridoxal 5'-phosphate)-binding barrel that can be found at the N terminus of alanine racemase-like proteins and members of the Orn/Lys/Arg decarboxylase class-II family of proteins.</p> <p>The molecular structure of alanine racemase from Bacillus stearothermophilus was determined by X-ray crystallography to a resolution of 1.9 A [[cite:PUB00000440]]. The alanine racemase monomer is composed of two domains, an eight-stranded α/β barrel at the N terminus, and a C-terminal domain essentially composed of β-strands. The pyridoxal 5'-phosphate (PLP) cofactor lies in and above the mouth of the α/β barrel and is covalently linked via an aldimine linkage to a lysine residue, which is at the C terminus of the first β-strand of the α/β barrel.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Ornithine decarboxylase [Lotus japonicus] gi|34495197|emb|CAE02644.1| | 22 | ||
| – | Ornithine decarboxylase [Lotus japonicus] gi|34495197|emb|CAE02644.1| | 21 | ||
| – | Arginine decarboxylase [Lotus japonicus] gi|34495199|emb|CAE02645.1| | 24 | ||
| – | Arginine decarboxylase [Lotus japonicus] gi|34495199|emb|CAE02645.1| | 19 | ||
| – | PREDICTED: diaminopimelate decarboxylase 1, chloroplastic-like [Cicer arietinum] gi|502161433|ref|XP_004512163.1| | 23 | ||
| – | PREDICTED: diaminopimelate decarboxylase 1, chloroplastic-like [Cicer arietinum] gi|502161433|ref|XP_004512163.1| | 22 | ||
| – | PREDICTED: arginine decarboxylase-like [Cicer arietinum] gi|502149391|ref|XP_004507509.1| | 29 | ||
| – | PREDICTED: proline synthase co-transcribed bacterial homolog protein-like isoform X1 [Cicer arietinum] gi|502166388|ref|XP_004513878.1| | 12 | ||
| – | PREDICTED: proline synthase co-transcribed bacterial homolog protein-like [Cicer arietinum] gi|502079184|ref|XP_004486181.1| | 9 | ||
| – | Ornithine decarboxylase; TAIR: AT3G14390.1 Pyridoxal-dependent decarboxylase family protein; Swiss-Prot: sp|P50134|DCOR_DATST Ornithine decarboxylase; TrEMBL-Plants: tr|Q70KF6|Q70KF6_LOTJA Ornithine decarboxylase; Found in the gene: LotjaGi1g1v0432800 | 22 | ||
| – | Arginine decarboxylase; TAIR: AT4G34710.1 arginine decarboxylase 2; Swiss-Prot: sp|Q39827|SPE1_SOYBN Arginine decarboxylase; TrEMBL-Plants: tr|Q70KF5|Q70KF5_LOTJA Arginine decarboxylase; Found in the gene: LotjaGi1g1v0562700 | 22 | ||
| – | Diaminopimelate decarboxylase; TAIR: AT5G11880.1 Pyridoxal-dependent decarboxylase family protein; Swiss-Prot: sp|Q94A94|DCDA2_ARATH Diaminopimelate decarboxylase 2, chloroplastic; TrEMBL-Plants: tr|A0A151TUY1|A0A151TUY1_CAJCA Uncharacterized protein; Found in the gene: LotjaGi1g1v0690900 | 23 | ||
| – | Arginine decarboxylase; TAIR: AT2G16500.1 arginine decarboxylase 1; Swiss-Prot: sp|Q43075|SPE1_PEA Arginine decarboxylase; TrEMBL-Plants: tr|Q2PEQ1|Q2PEQ1_TRIPR Arginine decarboxylase; Found in the gene: LotjaGi3g1v0514900 | 28 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT4G26860.1 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q9Z2Y8|PROSC_MOUSE Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|A0A0S3S737|A0A0S3S737_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0156000 | 13 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT4G26860.1 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q9Z2Y8|PROSC_MOUSE Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|A0A0S3S737|A0A0S3S737_PHAAN Uncharacterized protein; Found in the gene: LotjaGi6g1v0156000 | 13 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT1G11930.2 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q3T0G5|PROSC_BOVIN Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|I3T823|I3T823_MEDTR Proline synthetase associated protein; Found in the gene: LotjaGi6g1v0290900 | 13 | ||
| – | Proline synthase co-transcribed bacterial; TAIR: AT4G26860.1 Putative pyridoxal phosphate-dependent enzyme, YBL036C type; Swiss-Prot: sp|Q3T0G5|PROSC_BOVIN Proline synthase co-transcribed bacterial homolog protein; TrEMBL-Plants: tr|I3T823|I3T823_MEDTR Proline synthetase associated protein; Found in the gene: LotjaGi6g1v0291200_LC | 6 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SSF51419 | SUPERFAMILY | 1 | 5.88 |