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IPR003251

Description

IPR003251 is a Rubrerythrin, diiron-binding domain.

<p>Rubrerythrin (Rr) is a fusion protein containing an N-terminal diiron-binding domain and a C-terminal domain homologous to rubredoxin [[cite:PUB00002663]]. This protein has been related to the response to oxidative stress [[cite:PUB00100839], [cite:PUB00100840], [cite:PUB00098338]].</p> <p>The 3-D structure of Desulphovibrio vulgaris rubrerythrin has been solved [[cite:PUB00008767]]. The structure reveals a tetramer of two-domain subunits. In each monomer, the N-terminal 146 residues form a four-α-helix bundle containing the diiron-oxo site (centre I), and the C-terminal 45 residues form a rubredoxin-like FeS4 domain.</p> <p>This entry represents the N-terminal diiron-binding domain of Rr, which has a has a ferritin-like fold [[cite:PUB00008767]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
Molecular function Metal ion binding Interacting selectively and non-covalently with any metal ion.
Biological process Oxidation-reduction process A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Magnesium-protoporphyrin IX monomethyl ester [oxidative] gi|255565372|ref|XP_002523677.1| 11
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase; TAIR: AT3G56940.1 dicarboxylate diiron protein, putative (Crd1); Swiss-Prot: sp|Q6SJV8|CRD1_GOSHI Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic; TrEMBL-Plants: tr|I3SCT7|I3SCT7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0654900 11
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase; TAIR: AT3G56940.1 dicarboxylate diiron protein, putative (Crd1); Swiss-Prot: sp|Q6SJV8|CRD1_GOSHI Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase, chloroplastic; TrEMBL-Plants: tr|I3SCT7|I3SCT7_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0654900 11

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 33.33