Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR004113

Description

IPR004113 is a FAD-binding oxidoreductase/transferase, type 4, C-terminal.

<p>This entry represents a domain found in a group of type 4 FAD-binding oxidoreductase/transferases and similar proteins from all cellular organisms, including D-2-hydroxyglutarate dehydrogenase from humans [[cite:PUB00103960]] and Escherichia coli [[cite:PUB00103958]], Alkyldihydroxyacetonephosphate synthase from Caenorhabditis elegans and D-2-hydroxyglutarate--pyruvate transhydrogenase DLD2 from Saccharomyces cerevisiae [[cite:PUB00103959]]. This domain, often found at the C-terminal end of the proteins, shows a ferredoxin-like fold [[cite:PUB00019533]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Catalytic activity Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
Molecular function Flavin adenine dinucleotide binding Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.

Associated Lotus transcripts 6

Transcript Name Description Predicted domains Domain count
PREDICTED: D-lactate dehydrogenase [cytochrome] gi|356505459|ref|XP_003521508.1| 17
PREDICTED: d-2-hydroxyglutarate dehydrogenase, mitochondrial-like [Cicer arietinum] gi|502161240|ref|XP_004512090.1| 17
D-lactate dehydrogenase, putative; TAIR: AT5G06580.1 FAD-linked oxidases family protein; Swiss-Prot: sp|Q94AX4|DLD_ARATH D-lactate dehydrogenase [cytochrome], mitochondrial; TrEMBL-Plants: tr|I1JQD0|I1JQD0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0741700 20
D-lactate dehydrogenase, putative; TAIR: AT5G06580.1 FAD-linked oxidases family protein; Swiss-Prot: sp|Q94AX4|DLD_ARATH D-lactate dehydrogenase [cytochrome], mitochondrial; TrEMBL-Plants: tr|A0A072U583|A0A072U583_MEDTR D-lactate dehydrogenase (Cytochrome); Found in the gene: LotjaGi1g1v0741700 9
D-2-hydroxyglutarate dehydrogenase, mitochondrial; TAIR: AT4G36400.1 FAD-linked oxidases family protein; Swiss-Prot: sp|O23240|D2HDH_ARATH D-2-hydroxyglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|G7KGB4|G7KGB4_MEDTR D-2-hydroxyglutarate dehydrogenase; Found in the gene: LotjaGi2g1v0385200 20
D-2-hydroxyglutarate dehydrogenase, mitochondrial; TAIR: AT4G36400.1 FAD-linked oxidases family protein; Swiss-Prot: sp|O23240|D2HDH_ARATH D-2-hydroxyglutarate dehydrogenase, mitochondrial; TrEMBL-Plants: tr|A0A0R0HMH0|A0A0R0HMH0_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0385200 13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF56176 SUPERFAMILY 1 16.67