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IPR004653

Source: InterPro

Description

IPR004653 is a tRNA-dihydrouridine(20/20a) synthase.

<p>Dihydrouridine (D) is a highly conserved modified base found in tRNAs from all domains of life. D is formed by reduction of the carbon-carbon double bond at positions 5 and 6 of the uridine base by dihydrouridine synthases (Dus), and is mostly found in the D-loop of tRNAs for which it is named [[cite:PUB00057678]].</p> <p>This entry represents DusA (also known as tRNA-dihydrouridine(20/20a) synthase), which specifically modifies U20 and U20a in tRNAs [[cite:PUB00057678]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0002943
Biological process TRNA dihydrouridine synthesis The process whereby a uridine in a transfer RNA is converted to dihydrouridine.
Subterm of
GO:0017150
Molecular function TRNA dihydrouridine synthase activity Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
LotjaGi3g1v0121800.1
– TRNA-dihydrouridine synthase; TAIR: AT5G47970.1 Aldolase-type TIM barrel family protein; Swiss-Prot: sp|Q9KUX9|DUSA_VIBCH tRNA-dihydrouridine(20/20a) synthase; TrEMBL-Plants: tr|K7LI80|K7LI80_SOYBN tRNA-dihydrouridine synthase; Found in the gene: LotjaGi3g1v0121800
Domains
13
LotjaGi3g1v0550700.1
– TRNA-dihydrouridine synthase; TAIR: AT3G63510.1 FMN-linked oxidoreductases superfamily protein; Swiss-Prot: sp|Q8Z1T1|DUSA_SALTI tRNA-dihydrouridine(20/20a) synthase; TrEMBL-Plants: tr|I3SNH2|I3SNH2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0550700
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd02801 CDD 1 50.00