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IPR005645 is a Serine hydrolase domain.
<p>This domain is found in a number of enzymes possessing esterase and hydrolase activity.</p> <p>This domain can be found in budding yeast Fsh1/2/3, fission yeast Dfr1 and the human OVCA2 protein. Fsh1/2/3 are putative serine hydrolases [[cite:PUB00055605]]. Dfr1 is a dihydrofolate reductase (DHFR) [[cite:PUB00079206]]. OVCA2 is a putative serine-hydrolase that has been linked to cancers [[cite:PUB00079205]]. Proteins containing this domain also includes Aspergillus terreus esterase LovG, which catalyzes the release of covalently bound dihydromonacolin L from LovB during lovastatin biosynthesis [[cite:PUB00079208]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: rhodanese-like domain-containing protein 6-like [Cicer arietinum] gi|502095190|ref|XP_004490394.1| | 7 | ||
| – | PREDICTED: abhydrolase domain-containing protein FAM108C1-like [Glycine max] gi|356513658|ref|XP_003525528.1| | 7 | ||
| – | Dihydrofolate reductase [Medicago truncatula] gi|357509019|ref|XP_003624798.1| | 8 | ||
| – | Ovarian cancer-associated gene 2 protein-like protein [Medicago truncatula] gi|357485613|ref|XP_003613094.1| | 7 | ||
| – | Ovarian cancer-associated gene 2 protein-like protein [Medicago truncatula] gi|357485613|ref|XP_003613094.1| | 6 | ||
| – | Ovarian cancer-associated gene 2 protein-like protein [Medicago truncatula] gi|357485613|ref|XP_003613094.1| | 6 | ||
| – | PREDICTED: rhodanese-like domain-containing protein 6-like [Cicer arietinum] gi|502116926|ref|XP_004495641.1| | 14 | ||
| – | Dihydrofolate reductase-like protein; TAIR: AT4G24380.1 dihydrofolate reductase; Swiss-Prot: sp|P36591|DYR_SCHPO Dihydrofolate reductase; TrEMBL-Plants: tr|I1JGX4|I1JGX4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0140200 | 7 | ||
| – | Dihydrofolate reductase; TAIR: AT4G24380.1 dihydrofolate reductase; Swiss-Prot: sp|P36591|DYR_SCHPO Dihydrofolate reductase; TrEMBL-Plants: tr|G7L2Q8|G7L2Q8_MEDTR Serine hydrolase; Found in the gene: LotjaGi1g1v0652700 | 8 | ||
| – | Dihydrofolate reductase; TAIR: AT4G24380.1 dihydrofolate reductase; Swiss-Prot: sp|P36591|DYR_SCHPO Dihydrofolate reductase; TrEMBL-Plants: tr|G7L2Q8|G7L2Q8_MEDTR Serine hydrolase; Found in the gene: LotjaGi1g1v0652700 | 8 | ||
| – | Dihydrofolate reductase-like protein; TAIR: AT5G65400.1 alpha/beta-Hydrolases superfamily protein; Swiss-Prot: sp|A4II73|OVCA2_XENTR Esterase OVCA2; TrEMBL-Plants: tr|A0A0B2NTL8|A0A0B2NTL8_GLYSO UPF0483 protein AGAP003155-like protein; Found in the gene: LotjaGi2g1v0325600_LC | 7 | ||
| – | Dihydrofolate reductase-like protein; TAIR: AT4G24380.1 dihydrofolate reductase; Swiss-Prot: sp|Q18169|LOVG_CAEEL Esterase C25G4.2; TrEMBL-Plants: tr|I3SQX9|I3SQX9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi2g1v0325700 | 7 | ||
| – | UPF0176 protein; TAIR: AT1G09280.1 rhodanese-like domain protein; Swiss-Prot: sp|Q94AC1|STR6_ARATH Rhodanese-like domain-containing protein 6; TrEMBL-Plants: tr|A0A072VNW1|A0A072VNW1_MEDTR Phospholipase/carboxylesterase family protein; Found in the gene: LotjaGi5g1v0231600 | 19 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd01518 | CDD | 1 | 7.69 |