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IPR006939 is a SNF5/SMARCB1/INI1.
<p>SNF5 is a component of the yeast SWI/SNF complex, which is an ATP-dependent nucleosome-remodelling complex that regulates the transcription of a subset of yeast genes. SNF5 is a key component of all SWI/SNF-class complexes characterised so far [[cite:PUB00008669]]. This family consists of the conserved region of SNF5, including a direct repeat motif. SNF5 is essential for the assembly promoter targeting and chromatin remodelling activity of the SWI-SNF complex [[cite:PUB00008670]]. SNF5 is also known as SMARCB1, for SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily b, member 1, and also INI1 for integrase interactor 1. Loss-of function mutations in SNF5 are thought to contribute to oncogenesis in malignant rhabdoid tumours (MRTs) [[cite:PUB00008671]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Nuclear chromosome | A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact. | ||
| Biological process | Chromatin remodeling | Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Chromatin structure-remodeling complex protein BSH-like [Glycine max] gi|359806723|ref|NP_001241294.1| | 3 | ||
| – | Chromatin structure-remodeling complex protein BSH [Medicago truncatula] gi|357479241|ref|XP_003609906.1| | 3 | ||
| – | SNF5 [Pisum sativum] gi|107857310|gb|ABF85669.1| | 3 | ||
| – | Bushy growth protein; TAIR: AT3G17590.3 transcription regulatory protein SNF5, putative (BSH); Swiss-Prot: sp|P93045|BSH_ARATH Chromatin structure-remodeling complex protein BSH; TrEMBL-Plants: tr|A0A0L9TSB3|A0A0L9TSB3_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0010000_LC | 9 | ||
| – | Bushy growth protein; TAIR: AT3G17590.1 transcription regulatory protein SNF5, putative (BSH); Swiss-Prot: sp|P93045|BSH_ARATH Chromatin structure-remodeling complex protein BSH; TrEMBL-Plants: tr|I3S717|I3S717_LOTJA Uncharacterized protein; Found in the gene: LotjaGi4g1v0317300 | 4 | ||
| – | Bushy growth protein; TAIR: AT3G17590.3 transcription regulatory protein SNF5, putative (BSH); Swiss-Prot: sp|P93045|BSH_ARATH Chromatin structure-remodeling complex protein BSH; TrEMBL-Plants: tr|I3S717|I3S717_LOTJA Uncharacterized protein; Found in the gene: LotjaGi6g1v0131300_LC | 3 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| PTHR10019 | PANTHER | 1 | 16.67 |