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GO:0006325

Overview

Field Value
Namespace Biological process
Short description Chromatin organization
Full defintion Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
Subterm of

Relationships

The relationship of GO:0006325 with other GO terms.

Relationship type GO terms
Is a
Regulates n.a.
Part of
Positively regulates n.a.
Negatively regulates n.a.

Ancestor tree

A force layout showing the ancestor tree for GO:0006325, and its immediate children. If you wish to explore the tree dynamically, please use the GO Explorer.

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Additional data

This table contains additional metadata associated with the GO entry's definition field.

Field Value
GOCvw
PMID
Characterization of the RNA content of chromatin.
Genome Res. ; 20 (7): 899–907.PMID: 20404130

Noncoding RNA (ncRNA) constitutes a significant portion of the mammalian transcriptome. Emerging evidence suggests that it regulates gene expression in cis or trans by modulating the chromatin structure. To uncover the functional role of ncRNA in chromatin organization, we deep sequenced chromatin-associated RNAs (CARs) from human fibroblast (HF) cells. This resulted in the identification of 141 intronic regions and 74 intergenic regions harboring CARs. The intronic and intergenic CARs show significant conservation across 44 species of placental mammals. Functional characterization of one of the intergenic CARs, Intergenic10, revealed that it regulates gene expression of neighboring genes through modulating the chromatin structure in cis. Our data suggest that ncRNA is an integral component of chromatin and that it may regulate various biological functions through fine-tuning of the chromatin architecture.

Associated Lotus transcripts 16

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

Transcript Name Description GO terms GO count
PREDICTED: protein HIRA-like [Glycine max] gi|356543582|ref|XP_003540239.1| 3
PREDICTED: nuA4 complex subunit EAF3 homolog [Glycine max] gi|356510513|ref|XP_003523982.1| 3
PREDICTED: protein HIRA-like isoform X1 [Cicer arietinum] gi|502145733|ref|XP_004506155.1| 3
PREDICTED: histone acetyltransferase type B catalytic subunit-like [Glycine max] gi|356551642|ref|XP_003544183.1| 1
PREDICTED: protein HIRA-like [Glycine max] gi|356543582|ref|XP_003540239.1| 3
PREDICTED: nuA4 complex subunit EAF3 homolog [Glycine max] gi|356511911|ref|XP_003524665.1| 3
Histone acetyltransferase; TAIR: AT5G56740.1 histone acetyltransferase of the GNAT family 2; Swiss-Prot: sp|Q9FJT8|HATB_ARATH Histone acetyltransferase type B catalytic subunit; TrEMBL-Plants: tr|I1M828|I1M828_SOYBN Histone acetyltransferase; Found in the gene: LotjaGi1g1v0086700 1
Mortality factor 4-like protein 1; TAIR: AT1G02740.1 MRG family protein; Swiss-Prot: sp|Q4V3E2|MRG2_ARATH Protein MRG2; TrEMBL-Plants: tr|A0A151TTR4|A0A151TTR4_CAJCA Chromatin modification-related protein eaf3; Found in the gene: LotjaGi1g1v0358500 3
Mortality factor 4-like protein 1; TAIR: AT1G02740.1 MRG family protein; Swiss-Prot: sp|Q4V3E2|MRG2_ARATH Protein MRG2; TrEMBL-Plants: tr|A0A0B2PA75|A0A0B2PA75_GLYSO Chromatin modification-related protein EAF3; Found in the gene: LotjaGi1g1v0358500 3
WD-repeat protein, putative; TAIR: AT3G44530.2 histone chaperone HIRA-like protein; Swiss-Prot: sp|Q9LXN4|HIRA_ARATH Protein HIRA; TrEMBL-Plants: tr|K7LVP9|K7LVP9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0175400 3
WD-repeat protein, putative; TAIR: AT3G44530.2 histone chaperone HIRA-like protein; Swiss-Prot: sp|Q9LXN4|HIRA_ARATH Protein HIRA; TrEMBL-Plants: tr|K7LVP9|K7LVP9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0175400 3
Protein HIRA; TAIR: AT3G44530.3 histone chaperone HIRA-like protein; Swiss-Prot: sp|Q9LXN4|HIRA_ARATH Protein HIRA; TrEMBL-Plants: tr|K7LVP9|K7LVP9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0175400 3
Mortality factor 4-like protein 1; TAIR: AT4G37280.1 MRG family protein; Swiss-Prot: sp|Q94C32|MRG1_ARATH Protein MRG1; TrEMBL-Plants: tr|I1K283|I1K283_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0099900 3
Mortality factor 4-like protein 1; TAIR: AT4G37280.1 MRG family protein; Swiss-Prot: sp|Q94C32|MRG1_ARATH Protein MRG1; TrEMBL-Plants: tr|I1K283|I1K283_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0099900 3
Mortality factor 4-like protein 1; TAIR: AT4G37280.1 MRG family protein; Swiss-Prot: sp|Q94C32|MRG1_ARATH Protein MRG1; TrEMBL-Plants: tr|I1K283|I1K283_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0099900 3
Mortality factor 4-like protein 1; TAIR: AT4G37280.1 MRG family protein; Swiss-Prot: sp|Q94C32|MRG1_ARATH Protein MRG1; TrEMBL-Plants: tr|I1K283|I1K283_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0100000_LC 3

Co-occuring GO terms 1

A list of co-occurring GO terms within the L. japonicus gene space:

GO term Namespace Name Observations Saturation (%)
Biological process Regulation of transcription, DNA-templated 1 6.25