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IPR007320 is a Programmed cell death protein 2, C-terminal.
<p>PDCD2 is localized predominantly in the cytosol of cells situated at the opposite pole of the germinal centre from the centroblasts as well as in cells in the mantle zone. It has been shown to interact with BCL6, an evolutionarily conserved Kruppel-type zinc finger protein that functions as a strong transcriptional repressor and is required for germinal centre development. The rat homologue, Rp8, is associated with programmed cell death in thymocytes.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Cytoplasm | All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: programmed cell death protein 2-like [Glycine max] gi|356509030|ref|XP_003523255.1| | 3 | ||
| – | PREDICTED: LOW QUALITY PROTEIN: programmed cell death protein 2-like [Glycine max] gi|356542551|ref|XP_003539730.1| | 4 | ||
| – | Programmed cell death protein 2-like protein; TAIR: AT5G64830.1 programmed cell death 2 C-terminal domain-containing protein; Swiss-Prot: sp|Q5ZID2|PDD2L_CHICK Programmed cell death protein 2-like; TrEMBL-Plants: tr|A0A0S3REK6|A0A0S3REK6_PHAAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0312400 | 3 | ||
| – | Programmed cell death protein 2; TAIR: AT4G02220.1 zinc finger (MYND type) family protein / programmed cell death 2 C-terminal domain-containing protein; Swiss-Prot: sp|Q16342|PDCD2_HUMAN Programmed cell death protein 2; TrEMBL-Plants: tr|C6TKD7|C6TKD7_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi1g1v0641900 | 10 | ||
| – | Programmed cell death protein 2; TAIR: AT4G02220.1 zinc finger (MYND type) family protein / programmed cell death 2 C-terminal domain-containing protein; Swiss-Prot: sp|Q2YDC9|PDCD2_BOVIN Programmed cell death protein 2; TrEMBL-Plants: tr|C6TKD7|C6TKD7_SOYBN Putative uncharacterized protein; Found in the gene: LotjaGi6g1v0314800 | 10 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 20.00 |