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IPR007528 is a RINT-1/Tip20.
<p>This entry includes RINT-1 from animals, Tip20 from yeasts and MAIGO2 (Mag2) from plants. They play a role in anterograde transport from the endoplasmic reticulum (ER) to the Golgi and/or retrograde transport from the Golgi to the ER share sequence similarity [[cite:PUB00100047]]. They are part of the CATCHR (complexes associated with tethering containing helical rods) family which comprises the exocyst, COG, GARP, and DSL1 complexes and share a similar structure organisation with an N-terminal coiled-coil and a C-terminal α-helical bundle, which might be a protein-protein interaction module necessary for the formation of functional complexes.</p> <p>RINT-1 interacts with Rad50 only during late S and G2/M phases and participates in radiation induced checkpoint control [[cite:PUB00010117]]. RINT-1 also functions in membrane trafficking from the endoplasmic reticulum (ER) to the Golgi complex in interphase cells [[cite:PUB00010117], [cite:PUB00043787], [cite:PUB00043788]].</p> <p>Tip20 is involved in the retrograde transport from the Golgi to the ER [[cite:PUB00051798], [cite:PUB00010001]].</p> <p>Arabidopsis Mag2 functions in the transport of storage protein precursors between the ER and Golgi complex in plants [[cite:PUB00072705], [cite:PUB00072936]].</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Cellular component | Endoplasmic reticulum | The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached). | ||
| Biological process | Golgi vesicle transport | The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: RINT1-like protein-like [Glycine max] gi|356510640|ref|XP_003524045.1| | 6 | ||
| – | RINT-1 / TIP-1 family protein [Arabidopsis thaliana] gi|30680623|ref|NP_172316.2| | 5 | ||
| – | RINT-1 / TIP-1 family protein [Arabidopsis thaliana] gi|30680623|ref|NP_172316.2| | 5 | ||
| – | 30S ribosomal protein S15; TAIR: AT3G47700.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q9STU3|MAG2_ARATH RINT1-like protein MAG2; TrEMBL-Plants: tr|A0A1J7GL55|A0A1J7GL55_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0583600 | 6 | ||
| – | 30S ribosomal protein S15; TAIR: AT3G47700.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q9STU3|MAG2_ARATH RINT1-like protein MAG2; TrEMBL-Plants: tr|A0A1J7GL55|A0A1J7GL55_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0583600 | 7 | ||
| – | 30S ribosomal protein S15; TAIR: AT3G47700.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q9STU3|MAG2_ARATH RINT1-like protein MAG2; TrEMBL-Plants: tr|A0A1J7GL55|A0A1J7GL55_LUPAN Uncharacterized protein; Found in the gene: LotjaGi1g1v0583600 | 6 | ||
| – | RINT-1/TIP-1 family protein; TAIR: AT1G08400.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q8GXP1|MAG2L_ARATH RINT1-like protein MAG2L; TrEMBL-Plants: tr|V7BJQ4|V7BJQ4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0188400 | 4 | ||
| – | RINT-1/TIP-1 family protein; TAIR: AT1G08400.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q8GXP1|MAG2L_ARATH RINT1-like protein MAG2L; TrEMBL-Plants: tr|A0A0R0E6T9|A0A0R0E6T9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0188400 | 9 | ||
| – | RINT-1/TIP-1 family protein; TAIR: AT1G08400.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q8GXP1|MAG2L_ARATH RINT1-like protein MAG2L; TrEMBL-Plants: tr|A0A072V5P0|A0A072V5P0_MEDTR RINT-1/TIP-1 family protein; Found in the gene: LotjaGi6g1v0188400 | 4 | ||
| – | RINT-1/TIP-1 family protein; TAIR: AT1G08400.1 RINT-1 / TIP-1 family; Swiss-Prot: sp|Q8GXP1|MAG2L_ARATH RINT1-like protein MAG2L; TrEMBL-Plants: tr|A0A0R0E6T9|A0A0R0E6T9_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0188400 | 9 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| SIGNAL_PEPTIDE_N_REGION | Phobius | 1 | 10.00 |