Description

IPR009040 is a Ferritin-like diiron domain.

<p>This entry represents a group of proteins, containing ferritin-like domain, which is an about 145-residue domain made of a four-helix bundle surrounding a non-heme, non-sulphur, oxo-bridged diiron site. The diiron site is contained within a twisted, left-handed four- helix-bundle constituted of two anti-parallel helix pairs connected through a left-handed crossover connection. Known ligand residues at non-heme, non- sulphur diiron sites in proteins include His, Asp, Glu, and Tyr. Proteins containing a ferritin-like diiron domain possess the ability to catalyze oxidation of Fe²⁺to Fe²⁺by O₂, i.e. ferroxidase activity. The ferritin- like diiron domain occurs in stand-alone form in ferritin and bacterioferritin or in association with the rubredoxin-like domain in rubrerythrin [[cite:PUB00008767]]. Proteins known to contain a ferritin-like diiron domain are listed below:</p> <ul><li>Ferritin (Ftn), an eukaryotic intracellular protein that stores iron in a soluble, nontoxic, readily available form.</li> <li>Bacterioferritin (Bfr), a prokaryotic protein which may perform functions in iron detoxification and storage.</li> <li>Rubrerythrin (Rr), a non-heme protein isolated from anaerobic sulphate- reducing bacteria.</li> <li>Nigerythrin (Nr), a prokaryotic protein of unknown function.</li></ul>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 5

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: