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IPR010021 is a Phosphatidylglycerophosphate phosphatase.
<p>This group of proteins is a part of the IIIA subfamily of the haloacid dehalogenase (HAD) superfamily of hydrolases. All characterised members of this subfamily and most characterised members of the HAD superfamily are phosphatases. HAD superfamily phosphatases contain active site residues in several conserved catalytic motifs [[cite:PUB00003337]], all of which are found conserved here.</p> <p>This family consists of sequences from fungi, plants, cyanobacteria, Gram-positive bacteria and Deinococcus. Proteins in this entry Includes phosphatidylglycerophosphatase Gep4 from budding yeasts and phosphatidylglycerophosphate phosphatase 1 (PGPP1) from plants. Gep4 is involved in the biosynthesis of cardiolipin and phosphatidylethanolamine for survival of prohibitin-deficient cells [[cite:PUB00066888], [cite:PUB00066452]]. Chloroplastic PGPP1 is involved in the biosynthesis of phosphatidylglycerol (PG), a phosphoglycerolipid present in chloroplastic thylakoid membranes and has a photosynthetic function [[cite:PUB00094223]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: phosphatidylglycerophosphatase GEP4, mitochondrial-like isoform X1 [Cicer arietinum] gi|502134114|ref|XP_004502005.1| | 12 | ||
| – | Haloacid dehalogenase superfamily protein [Phaseolus vulgaris] gi|396582339|gb|AFN88203.1| | 13 | ||
| – | Haloacid dehalogenase superfamily protein; TAIR: AT3G58830.2 haloacid dehalogenase (HAD) superfamily protein; Swiss-Prot: sp|P38812|GEP4_YEAST Phosphatidylglycerophosphatase GEP4, mitochondrial; TrEMBL-Plants: tr|I1JWJ8|I1JWJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0193600 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 33.33 |