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IPR027706

Source: InterPro

Description

IPR027706 is a PGP phosphatase, mitochondrial/chloroplastic.

<p>Mitochondrial phosphatidylglycerophosphatase (PGP phosphatase) ([ec:3.1.3.27]) dephosphorylates phosphatidylglycerolphosphate to generate phosphatidylglycerol in cardiolipin biosynthesis. Cardiolipin is a unique dimeric phosphoglycerolipid predominantly present in mitochondrial membranes. The inverted phosphatase motif includes the highly conserved DKD triad [[cite:PUB00066452], [cite:PUB00066888]]. In Saccharomyces cerevisiae, Gep4 is required for the stability of respiratory chain supercomplexes and for growth at elevated temperature, in presence of ethidium bromide or in absence of prohibitins [[cite:PUB00066452]].</p> <p>Chloroplastic phosphatidylglycerophosphate phosphatase is involved in the biosynthesis of phosphatidylglycerol (PG), a phosphoglycerolipid present in chloroplastic thylakoid membranes and has a photosynthetic function [[cite:PUB00094223]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 3

Transcript Name Description Predicted domains Domain count
Lj0g3v0251799.1
– PREDICTED: phosphatidylglycerophosphatase GEP4, mitochondrial-like isoform X1 [Cicer arietinum] gi|502134114|ref|XP_004502005.1|
Domains
12
Lj0g3v0251799.2
– Haloacid dehalogenase superfamily protein [Phaseolus vulgaris] gi|396582339|gb|AFN88203.1|
Domains
13
LotjaGi6g1v0193600.1
– Haloacid dehalogenase superfamily protein; TAIR: AT3G58830.2 haloacid dehalogenase (HAD) superfamily protein; Swiss-Prot: sp|P38812|GEP4_YEAST Phosphatidylglycerophosphatase GEP4, mitochondrial; TrEMBL-Plants: tr|I1JWJ8|I1JWJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0193600
Domains
13

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 33.33