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IPR006549 is a HAD-superfamily hydrolase,subfamily IIIA.
<p>This group of proteins is a part of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The Class III subfamilies are characterised by the lack of any domains located either between the first and second conserved catalytic motifs (as in the Class I subfamilies) or between the second and third conserved catalytic motifs (as in the Class II subfamilies) of the superfamily domain [[cite:PUB00003337], [cite:PUB00009589]]. The IIIA subfamily contains five major clades: histidinol-phosphatase [[cite:PUB00009674]], histidinol-phosphatase-related protein, DNA 3-phosphatase and sequences related to YqeG and YrbI.</p> <p>In the case of histidinol phosphatase and PNK-3'-phosphatase, this entry represents a domain of a bifunctional system. In the histidinol phosphatase HisB, a C-terminal domain is an imidazoleglycerol-phosphate dehydratase which catalyses a related step in histidine biosynthesis [[cite:PUB00009674]]. In PNK-3'-phosphatase, N- and C-terminal domains constitute the polynucleotide kinase and DNA-binding components of the enzyme.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: polynucleotide 3'-phosphatase ZDP-like isoform X1 [Cicer arietinum] gi|502177429|ref|XP_004516081.1| | 20 | ||
| – | PREDICTED: phosphatidylglycerophosphatase GEP4, mitochondrial-like isoform X1 [Cicer arietinum] gi|502134114|ref|XP_004502005.1| | 12 | ||
| – | Haloacid dehalogenase superfamily protein [Phaseolus vulgaris] gi|396582339|gb|AFN88203.1| | 13 | ||
| – | PREDICTED: polynucleotide 3'-phosphatase ZDP-like isoform X1 [Cicer arietinum] gi|502177429|ref|XP_004516081.1| | 20 | ||
| – | Poly [ADP]-ribose] polymerase; TAIR: AT3G14890.1 phosphoesterase; Swiss-Prot: sp|Q84JE8|ZDP_ARATH Polynucleotide 3'-phosphatase ZDP; TrEMBL-Plants: tr|I3S6I9|I3S6I9_LOTJA Uncharacterized protein; Found in the gene: LotjaGi3g1v0041600 | 22 | ||
| – | Haloacid dehalogenase superfamily protein; TAIR: AT3G58830.2 haloacid dehalogenase (HAD) superfamily protein; Swiss-Prot: sp|P38812|GEP4_YEAST Phosphatidylglycerophosphatase GEP4, mitochondrial; TrEMBL-Plants: tr|I1JWJ8|I1JWJ8_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0193600 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |