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IPR010643 is a Helical and beta-bridge domain.
<p>HBB is the domain on DEAD-box eukaryotic DNA repair helicases ([ec:3.6.1.-]) that appears to be a unique fold. It's conformation is of α-helices 12-16 plus a short β-bridge to the FeS-cluster domain at the N-terminal. The full-length XPD protein verifies the presence of damage to DNA and allows DNA repair to proceed. XPD is an assembly of several domains to form a doughnut-shaped molecule that is able to separate two DNA strands and scan the DNA for damage. HBB helps to form the overall DNA-clamping architecture [[cite:PUB00049879]]. This family represents a conserved region within a number of eukaryotic and prokaryotic DNA repair helicases ([ec:3.6.1.-]).</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | DNA repair helicase; TAIR: AT1G03190.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q8W4M7|ERCC2_ARATH DNA repair helicase XPD; TrEMBL-Plants: tr|A0A072VC04|A0A072VC04_MEDTR DNA repair helicase (Rad3); Found in the gene: LotjaGi2g1v0132200 | 14 | ||
| – | DNA repair helicase; TAIR: AT1G03190.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q8W4M7|ERCC2_ARATH DNA repair helicase XPD; TrEMBL-Plants: tr|A0A0L9VKH8|A0A0L9VKH8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0132200 | 24 | ||
| – | DNA repair helicase; TAIR: AT1G03190.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q8W4M7|ERCC2_ARATH DNA repair helicase XPD; TrEMBL-Plants: tr|A0A0L9VKH8|A0A0L9VKH8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0132200 | 23 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd18788 | CDD | 1 | 33.33 |