Your browser is unable to support new features implemented in HTML5 and CSS3 to render this site as intended. Your experience may suffer from functionality degradation but the site should remain usable. We strongly recommend the latest version of Google Chrome, OS X Safari or Mozilla Firefox. As Safari is bundled with OS X, if you are unable to upgrade to a newer version of OS X, we recommend using an open source browser. Dismiss message

IPR013020

Source: InterPro

Description

IPR013020 is a ATP-dependent helicase Rad3/Chl1-like.

<p>This entry includes a group of ATP-dependent helicases, including Rad3/XPD (ERCC2), Chl1/DDX11, DDX12, RTEL1 and BRIP1. Rad3/XPD is a subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3) [[cite:PUB00062838], [cite:PUB00056880]]. DDX11/Chl1 is required for sister-chromatid cohesion [[cite:PUB00062839], [cite:PUB00062840], [cite:PUB00062845]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0003678
Molecular function DNA helicase activity Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
Subterm of

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj0g3v0292829.1
– ATP-dependent RNA helicase chl1 [Medicago truncatula] gi|357468391|ref|XP_003604480.1|
Domains
10
Lj0g3v0292829.2
– PREDICTED: probable ATP-dependent RNA helicase DDX11-like isoform X2 [Cicer arietinum] gi|502147607|ref|XP_004506847.1|
Domains
18
LotjaGi2g1v0132200.1
– DNA repair helicase; TAIR: AT1G03190.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q8W4M7|ERCC2_ARATH DNA repair helicase XPD; TrEMBL-Plants: tr|A0A072VC04|A0A072VC04_MEDTR DNA repair helicase (Rad3); Found in the gene: LotjaGi2g1v0132200
Domains
14
LotjaGi2g1v0132200.2
– DNA repair helicase; TAIR: AT1G03190.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q8W4M7|ERCC2_ARATH DNA repair helicase XPD; TrEMBL-Plants: tr|A0A0L9VKH8|A0A0L9VKH8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0132200
Domains
24
LotjaGi2g1v0132200.3
– DNA repair helicase; TAIR: AT1G03190.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|Q8W4M7|ERCC2_ARATH DNA repair helicase XPD; TrEMBL-Plants: tr|A0A0L9VKH8|A0A0L9VKH8_PHAAN Uncharacterized protein; Found in the gene: LotjaGi2g1v0132200
Domains
23
LotjaGi3g1v0366000.1
– Rad3-related DNA helicase family protein; TAIR: AT1G79890.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|F1R345|DDX11_DANRE ATP-dependent DNA helicase DDX11; TrEMBL-Plants: tr|I1KG67|I1KG67_SOYBN Uncharacterized protein; Found in the gene: LotjaGi3g1v0366000
Domains
24
LotjaGi3g1v0366000.2
– Rad3-related DNA helicase family protein; TAIR: AT1G79890.1 RAD3-like DNA-binding helicase protein; Swiss-Prot: sp|F1R345|DDX11_DANRE ATP-dependent DNA helicase DDX11; TrEMBL-Plants: tr|A0A072TSN1|A0A072TSN1_MEDTR Rad3-related DNA helicase family protein; Found in the gene: LotjaGi3g1v0366000
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
cd18788 CDD 1 14.29