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IPR010977

Source: InterPro

Description

IPR010977 is a Aromatic-L-amino-acid decarboxylase.

<p>A number of pyridoxal-dependent decarboxylases share regions of sequence similarity, particularly in the vicinity of a conserved lysine residue, which provides the attachment site for the pyridoxal-phosphate (PLP) group [[cite:PUB00001452], [cite:PUB00003414]]. Among these enzymes are aromatic-L-amino-acid decarboxylase (L-dopa decarboxylase or tryptophan decarboxylase), which catalyses the decarboxylation of tryptophan to tryptamine [[cite:PUB00002358]]; tyrosine decarboxylase, which converts tyrosine into tyramine; and histidine decarboxylase, which catalyses the decarboxylation of histidine to histamine [[cite:PUB00004715]]. These enzymes belong to the group II decarboxylases [[cite:PUB00001452], [cite:PUB00002358]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0006520
Biological process Cellular amino acid metabolic process The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
Subterm of
GO:0016831
Molecular function Carboxy-lyase activity Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
Subterm of

Associated Lotus transcripts 7

Transcript Name Description Predicted domains Domain count
Lj0g3v0211149.1
– PREDICTED: tyrosine/DOPA decarboxylase 2-like [Glycine max] gi|356522542|ref|XP_003529905.1|
Domains
15
Lj1g3v4528440.1
– PREDICTED: tyrosine decarboxylase 1-like [Cicer arietinum] gi|502110253|ref|XP_004493836.1|
Domains
16
Lj6g3v1679480.1
– PREDICTED: tyrosine/DOPA decarboxylase 2-like [Glycine max] gi|356558045|ref|XP_003547319.1|
Domains
15
LotjaGi1g1v0703100.1
– Tyrosine decarboxylase family protein; TAIR: AT2G20340.1 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein; Swiss-Prot: sp|Q8RY79|TYDC1_ARATH Tyrosine decarboxylase 1; TrEMBL-Plants: tr|G7KYF4|G7KYF4_MEDTR Tyrosine/DOPA decarboxylase; Found in the gene: LotjaGi1g1v0703100
Domains
16
LotjaGi3g1v0391700.1
– Tyrosine decarboxylase; TAIR: AT2G20340.1 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein; Swiss-Prot: sp|P54769|TYDC2_PAPSO Tyrosine/DOPA decarboxylase 2; TrEMBL-Plants: tr|A0A0B2R021|A0A0B2R021_GLYSO Tyrosine/DOPA decarboxylase 2; Found in the gene: LotjaGi3g1v0391700
Domains
15
LotjaGi6g1v0274400.1
– Tyrosine decarboxylase; TAIR: AT2G20340.1 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein; Swiss-Prot: sp|P54769|TYDC2_PAPSO Tyrosine/DOPA decarboxylase 2; TrEMBL-Plants: tr|V7AQJ2|V7AQJ2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0274400
Domains
13
LotjaGi6g1v0274400.2
– Tyrosine decarboxylase; TAIR: AT2G20340.1 Pyridoxal phosphate (PLP)-dependent transferases superfamily protein; Swiss-Prot: sp|P54769|TYDC2_PAPSO Tyrosine/DOPA decarboxylase 2; TrEMBL-Plants: tr|V7AQJ2|V7AQJ2_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0274400
Domains
15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
SSF53383 SUPERFAMILY 1 14.29