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IPR011422

Source: InterPro

Description

IPR011422 is a BRCA1-associated 2/ETP1, RRM.

<p>This entry represents the RNA-binding domain (also referred to as RNA recognition motif (RRM)) of BRAP2 and its homologues.</p> <p>This entry includes human BRCA1-associated protein (BRAP/BRAP2, also known as impedes mitogenic signal propagation (IMP), RING finger protein 52, or renal carcinoma antigen NY-REN-63) and its homologues from yeast ETP1. BRAP2 is a cytoplasmic protein interacting with the two functional nuclear localization signal (NLS) motifs of BRCA1, a nuclear protein linked to breast cancer. It also binds to the SV40 large T antigen NLS motif and the bipartite NLS motif found in mitosin. BRAP2 serves as a cytoplasmic retention protein and plays a role in the regulation of nuclear protein transport [[cite:PUB00014718], [cite:PUB00033420], [cite:PUB00054094], [cite:PUB00084647], [cite:PUB00084644], [cite:PUB00084641]].</p> <p>These proteins contain an N-terminal RNA recognition motif (RRM), also known as RBD (RNA binding domain) or RNP (ribonucleoprotein domain), followed by a C3H2C3-type RING-H2 finger and a UBP-type zinc finger.</p>

This description is obtained from EB-eye REST.

Associated GO terms

Unable to find any GO terms for the transcript with the identifier.

Associated Lotus transcripts 4

Transcript Name Description Predicted domains Domain count
Lj3g3v0030640.1
– PREDICTED: BRCA1-associated protein-like [Cicer arietinum] gi|502080643|ref|XP_004486630.1|
Domains
19
Lj4g3v1881410.1
– PREDICTED: BRCA1-associated protein-like [Glycine max] gi|356562985|ref|XP_003549748.1|
Domains
16
Lj4g3v1881410.2
– PREDICTED: BRCA1-associated protein-like [Glycine max] gi|356562985|ref|XP_003549748.1|
Domains
16
LotjaGi4g1v0273800.1
– BRCA1-associated protein; TAIR: AT2G42160.1 zinc finger (ubiquitin-hydrolase) domain-containing protein; Swiss-Prot: sp|Q7Z569|BRAP_HUMAN BRCA1-associated protein; TrEMBL-Plants: tr|I1MU69|I1MU69_SOYBN Uncharacterized protein; Found in the gene: LotjaGi4g1v0273800
Domains
17

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 25.00