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IPR011877

Description

IPR011877 is a Ribokinase.

<p>This entry describes ribokinase, an enzyme catalysing the first step in ribose catabolism. This phosphorylation of ribose to ribose-5-phosphate using ATP traps ribose within the cell after uptake and prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway [[cite:PUB00030699]]. The rbsK gene encoding ribokinase typically is found with ribose transport genes [[cite:PUB00078860]]. This entry also includes bifunctional ribokinase/ribose-5-phosphate isomerase A from Lactobacillus sanfranciscensis.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
Molecular function Ribokinase activity Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.
Biological process D-ribose metabolic process The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
PREDICTED: ribokinase-like isoform 1 [Glycine max] gi|356556858|ref|XP_003546737.1| 16
Ribokinase; TAIR: AT1G17160.1 pfkB-like carbohydrate kinase family protein; Swiss-Prot: sp|P44331|RBSK_HAEIN Ribokinase; TrEMBL-Plants: tr|A0A072VK36|A0A072VK36_MEDTR Ribokinase; Found in the gene: LotjaGi3g1v0257100 15

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00