Description

IPR002173 is a Carbohydrate/purine kinase, PfkB, conserved site.

<p>It has been shown [[cite:PUB00002140], [cite:PUB00004930], [cite:PUB00001797]] that the following carbohydrate and purine kinases are evolutionary related and can be grouped into a single family, which is known [[cite:PUB00002140]] as the 'pfkB family':</p> <ul> <li>Fructokinase ([ec:2.7.1.4]) (gene scrK).</li> <li>6-phosphofructokinase isozyme 2 ([ec:2.7.1.11]) (phosphofructokinase-2) (gene pfkB). pfkB is a minor phosphofructokinase isozyme in Escherichia coli and is not evolutionary related to the major isozyme (gene pfkA). Plant 6-phosphofructokinase also belong to this family.</li> <li>Ribokinase ([ec:2.7.1.15]) (gene rbsK).</li> <li>Adenosine kinase ([ec:2.7.1.20]) (gene ADK).</li> <li>2-dehydro-3-deoxygluconokinase ([ec:2.7.1.45]) (gene: kdgK).</li> <li>1-phosphofructokinase ([ec:2.7.1.56]) (fructose 1-phosphate kinase) (gene fruK).</li> <li>Inosine-guanosine kinase ([ec:2.7.1.73]) (gene gsk).</li> <li>Tagatose-6-phosphate kinase ([ec:2.7.1.144]) (phosphotagatokinase) (gene lacC).</li> <li>E. coli hypothetical protein yeiC.</li> <li>E. coli hypothetical protein yeiI.</li> <li>E. coli hypothetical protein yhfQ.</li> <li>E. coli hypothetical protein yihV.</li> <li>Yeast hypothetical protein YJR105w.</li></ul> <p>All the above kinases are proteins of from 280 to 430 amino acid residues that share a few region of sequence similarity.</p> <p>Note: some bacterial fructokinases belong to the ROK family (see [interpro:IPR000600]).</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on April 27, 2020, while the GO metadata was last updated on April 27, 2020.

Associated Lotus transcripts 48

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space: