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IPR013536 is a WLM domain.
<p>The WLM (WSS1-like metalloprotease) domain is a globular domain related to the zincin-like superfamily of Zn-dependent peptidase. Since the WLM domain contains all known active site residues of zincins, it is predicted to be a catalytically active peptidase domain. The WLM domain is a eukaryotic domain represented in plants, fungi, Plasmodium, and kinetoplastids. By contrast, it is absent in animals, Cryptosporidium, and Microsporidia, suggesting that it has been lost on multiple occasions during the evolution of eukaryotes. The WLM domain is found either in stand-alone form or in association with other domains such as the RanBP2 zinc finger , the ubiquitin domain, or the PUB/PUG domain. This domain could function as a specific de-SUMOylating domain of distinct protein complexes in the nucleus and the cytoplasm [[cite:PUB00020916]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Ubiquitin and WLM domain-containing protein [Medicago truncatula] gi|357469919|ref|XP_003605244.1| | 10 | ||
| – | PREDICTED: DNA damage response protein WSS1-like isoform X1 [Cicer arietinum] gi|502080507|ref|XP_004486586.1| | 12 | ||
| – | PREDICTED: DNA damage response protein WSS1-like [Cicer arietinum] gi|502123501|ref|XP_004498138.1| | 11 | ||
| – | PREDICTED: DNA damage response protein WSS1-like [Cicer arietinum] gi|502123501|ref|XP_004498138.1| | 11 | ||
| – | Ubiquitin and WLM domain-containing protein; TAIR: AT5G35690.1 zinc metalloproteinase-like protein; Swiss-Prot: sp|O94580|YQ77_SCHPO Ubiquitin and WLM domain-containing metalloprotease SPCC1442.07c; TrEMBL-Plants: tr|G7J8W3|G7J8W3_MEDTR Zinc metalloproteinase-like protein, putative; Found in the gene: LotjaGi6g1v0023600 | 15 | ||
| – | Zinc ion-binding protein; TAIR: AT1G55915.1 zinc ion binding protein; Swiss-Prot: sp|P38838|WSS1_YEAST DNA-dependent metalloprotease WSS1; TrEMBL-Plants: tr|A0A072V797|A0A072V797_MEDTR Zinc ion-binding protein; Found in the gene: LotjaGi6g1v0144400 | 13 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| mobidb-lite | MobiDBLite | 1 | 16.67 |