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IPR016154

Source: InterPro

Description

IPR016154 is a Heat shock protein Hsp33, C-terminal.

<p>This superfamily represents the C-terminal α/β domain from the heat shock protein Hsp33. Hsp33 is a molecular chaperone, distinguished from all other known chaperones by its mode of functional regulation. Its activity is redox regulated. Hsp33 is a cytoplasmically localised protein with highly reactive cysteines that respond quickly to changes in the redox environment. Oxidizing conditions like H<sub>2</sub>O<sub>2</sub>cause disulphide bonds to form in Hsp33, a process that leads to the activation of its chaperone function [[cite:PUB00000967]].</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0005737
Cellular component Cytoplasm All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
Subterm of
GO:0006457
Biological process Protein folding The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
Subterm of
GO:0051082
Molecular function Unfolded protein binding Interacting selectively and non-covalently with an unfolded protein.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj0g3v0215779.1
– HAT family dimerization domain containing protein [Medicago truncatula] gi|357498113|ref|XP_003619345.1|
Domains
3
Lj5g3v0817430.1
– HAT family dimerization domain containing protein [Medicago truncatula] gi|357498113|ref|XP_003619345.1|
Domains
10

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
mobidb-lite MobiDBLite 1 50.00