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IPR017870 is a FeS cluster insertion, C-terminal, conserved site.
<p>These proteins in this entry are small (106 to 135 amino-acid residues in bacteria, about 200 residues in fungi) that contain a number of conserved regions. They appear to be associated with the process of FeS-cluster assembly. The HesB proteins are associated with the nif gene cluster and the Rhizobium gene IscN has been shown to be required for nitrogen fixation [[cite:PUB00017348]]. Nitrogenase includes multiple FeS clusters and many genes for their assembly. The Escherichia coli SufA protein is associated with SufS, a NifS homologue and SufD which are involved in the FeS cluster assembly of the FhnF protein [[cite:PUB00010345]]. The Azotobacter protein IscA (homologues of which are also found in E. coli) is associated which IscS, another NifS homologue and IscU, a nifU homologue as well as other factors consistent with a role in FeS cluster chemistry [[cite:PUB00017349]]. A homologue from Geobacter contains a selenocysteine in place of an otherwise invariant cysteine, further suggesting a role in redox chemistry.</p> <p>This entry represents a conserved site in the C-terminal extremity, it contains two conserved cysteines.</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: iron-sulfur assembly protein IscA-like 1, mitochondrial-like [Cicer arietinum] gi|502111353|ref|XP_004494031.1| | 7 | ||
| – | PREDICTED: iron-sulfur assembly protein IscA, chloroplastic-like [Cicer arietinum] gi|502140001|ref|XP_004504011.1| | 11 | ||
| – | PREDICTED: iron-sulfur assembly protein IscA, chloroplastic-like [Cicer arietinum] gi|502140001|ref|XP_004504011.1| | 11 | ||
| – | Iron-sulfur cluster insertion protein erpA; TAIR: AT2G16710.1 Iron-sulfur cluster biosynthesis family protein; Swiss-Prot: sp|Q8LBM4|ISAM1_ARATH Iron-sulfur assembly protein IscA-like 1, mitochondrial; TrEMBL-Plants: tr|I1JQ14|I1JQ14_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0676300 | 11 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00049 | TIGRFAM | 1 | 25.00 |