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IPR000361 is a FeS cluster biogenesis.
<p>The proteins in this entry are variously annotated as iron-sulphur cluster insertion protein or Fe/S biogenesis protein. They appear to be involved in Fe-S cluster biogenesis. This family includes IscA, HesB, ErpA and SufA-like proteins. The hesB gene is expressed only under nitrogen fixation conditions [[cite:PUB00003602]]. IscA, an 11kDa member of the hesB family of proteins, binds iron and [2Fe-2S] clusters, and participates in the biosynthesis of iron-sulphur proteins. IscA is able to bind at least 2 iron ions per dimer [[cite:PUB00030961]].</p> <p>Other members of this family include various hypothetical proteins that also contain the NifU-like domain ([interpro:IPR001075]) suggesting that they too are able to bind iron and are involved in Fe-S cluster biogenesis. The HesB family are found in species as divergent as Homo sapiens (Human) and Haemophilus influenzae suggesting that these proteins are involved in basic cellular functions [[cite:PUB00003442]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: iron-sulfur assembly protein IscA-like 1, mitochondrial-like [Cicer arietinum] gi|502111353|ref|XP_004494031.1| | 7 | ||
| – | Iron-sulfur assembly protein IscA-like protein [Medicago truncatula] gi|357511065|ref|XP_003625821.1| | 9 | ||
| – | PREDICTED: iron-sulfur assembly protein IscA-like 2, mitochondrial-like isoform X1 [Cicer arietinum] gi|502111834|ref|XP_004494179.1| | 8 | ||
| – | PREDICTED: iron-sulfur assembly protein IscA, chloroplastic-like [Cicer arietinum] gi|502140001|ref|XP_004504011.1| | 11 | ||
| – | PREDICTED: iron-sulfur assembly protein IscA, chloroplastic-like [Cicer arietinum] gi|502140001|ref|XP_004504011.1| | 11 | ||
| – | Iron-sulfur cluster insertion protein ErpA; TAIR: AT5G03905.1 Iron-sulfur cluster biosynthesis family protein; Swiss-Prot: sp|Q8LCY2|ISAM2_ARATH Iron-sulfur assembly protein IscA-like 2, mitochondrial; TrEMBL-Plants: tr|I3SBC4|I3SBC4_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0675900 | 9 | ||
| – | Iron-sulfur cluster insertion protein erpA; TAIR: AT2G16710.1 Iron-sulfur cluster biosynthesis family protein; Swiss-Prot: sp|Q8LBM4|ISAM1_ARATH Iron-sulfur assembly protein IscA-like 1, mitochondrial; TrEMBL-Plants: tr|I1JQ14|I1JQ14_SOYBN Uncharacterized protein; Found in the gene: LotjaGi1g1v0676300 | 11 | ||
| – | Iron-sulfur cluster insertion protein ErpA; TAIR: AT5G03905.1 Iron-sulfur cluster biosynthesis family protein; Swiss-Prot: sp|Q8LCY2|ISAM2_ARATH Iron-sulfur assembly protein IscA-like 2, mitochondrial; TrEMBL-Plants: tr|I3SWV2|I3SWV2_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0741100 | 8 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00049 | TIGRFAM | 1 | 12.50 |