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IPR017958 is a Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site.
<p>Glutamyl-tRNA(Gln) amidotransferase (Gat; [ec:EC 6.3.5]) provides a means of producing correctly charged Gln-tRNA(Gln) through the transamidation of mis-acylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase [[cite:PUB00007932]]. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The enzyme is composed of three subunits: A (an amidase), B and C. It also exists in eukaryotes as a protein targeted to the mitochondria.</p> <p>The heterotrimer GatABC is involved in converting Glu to Gln and/or Asp to Asn, when the amino acid is attached to the appropriate tRNA. In Lactobacillus, GatABC is responsible for producing tRNA(Gln). In Archaea, GatABC is responsible for producing tRNA(Asn), while GatDE is responsible for producing tRNA(Gln). In lineages that include Thermus, Chlamydia, or Acidithiobacillus, the GatABC complex catalyses both tRNA(Gln) and tRNA(Asn).</p> <p>This entry represents a conserved region located in the N-terminal of the B subunit of glutamyl-tRNA(Gln) amidotransferase.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Carbon-nitrogen ligase activity, with glutamine as amido-N-donor | Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B-like [Glycine max] gi|356524618|ref|XP_003530925.1| | 22 | ||
| – | PREDICTED: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B-like [Glycine max] gi|356524618|ref|XP_003530925.1| | 22 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0219600 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0219600 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0219600 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0219600 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0219600 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0457900 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0457900 | 27 | ||
| – | Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TAIR: AT1G48520.1 GLU-ADT subunit B; Swiss-Prot: sp|B9SQR9|GATB_RICCO Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; TrEMBL-Plants: tr|I1KQC8|I1KQC8_SOYBN Glutamyl-tRNA(Gln) amidotransferase subunit B, chloroplastic/mitochondrial; Found in the gene: LotjaGi4g1v0457900 | 27 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TIGR00133 | TIGRFAM | 1 | 10.00 |