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IPR018050

Source: InterPro

Description

IPR018050 is a Phosphomannose isomerase, type I, conserved site.

<p>Phosphomannose isomerase (PMI) [[cite:PUB00001448], [cite:PUB00000378]] is the enzyme that catalyzes the interconversion of mannose-6-phosphate and fructose-6-phosphate. In eukaryotes, it is involved in the synthesis of GDP-mannose which is a constituent of N- and O-linked glycans as well as GPI anchors. In prokaryotes, it is involved in a variety of pathways including capsular polysaccharide biosynthesis and D-mannose metabolism.</p>

This description is obtained from EB-eye REST.

Associated GO terms

GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .

GO term Namespace Name Definition Relationships
GO:0004476
Molecular function Mannose-6-phosphate isomerase activity Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
Subterm of

Associated Lotus transcripts 2

Transcript Name Description Predicted domains Domain count
Lj0g3v0344639.1
– Phosphomannose isomerase [Cyamopsis tetragonoloba] gi|60617303|gb|AAX31279.1|
Domains
13
LotjaGi1g1v0549400.1
– Mannose-6-phosphate isomerase; TAIR: AT3G02570.1 Mannose-6-phosphate isomerase, type I; Swiss-Prot: sp|Q9M884|MPI1_ARATH Mannose-6-phosphate isomerase 1; TrEMBL-Plants: tr|Q5BMC5|Q5BMC5_CYATE Phosphomannose isomerase; Found in the gene: LotjaGi1g1v0549400
Domains
16

Co-occuring domains 1

A list of co-occurring predicted domains within the L. japonicus gene space:

Predicted domain Source Observations Saturation (%)
TIGR00218 TIGRFAM 1 50.00