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IPR018087 is a Glycoside hydrolase, family 5, conserved site.
<p>O-Glycosyl hydrolases ([ec:3.2.1.]) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families [[cite:PUB00004870], [cite:PUB00005266]]. This classification is available on the CAZy (CArbohydrate-Active EnZymes) website.</p> <p>Glycoside hydrolase family 5 [cazy:GH5] comprises enzymes with several known activities; endoglucanase ([ec:3.2.1.4]); beta-mannanase ([ec:3.2.1.78]); exo-1,3-glucanase ([ec:3.2.1.58]); endo-1,6-glucanase ([ec:3.2.1.75]); xylanase ([ec:3.2.1.8]); endoglycoceramidase ([ec:3.2.1.123]).</p> <p>The microbial degradation of cellulose and xylans requires several types of enzymes. Fungi and bacteria produces a spectrum of cellulolytic enzymes (cellulases) and xylanases which, on the basis of sequence similarities, can be classified into families. One of these families is known as the cellulase family A [[cite:PUB00001778]] or as the glycosyl hydrolases family 5 [[cite:PUB00000503]]. One of the conserved regions in this family contains a conserved glutamic acid residue which is potentially involved [[cite:PUB00004956]] in the catalytic mechanism.</p>
This description is obtained from EB-eye REST.
GO predictions are based solely on the InterPro-to-GO mappings published by EMBL-EBI, which are in turn based on the mapping of predicted domains to the InterPro dataset. The InterPro-to-GO mapping was last updated on , while the GO metadata was last updated on .
| GO term | Namespace | Name | Definition | Relationships |
|---|---|---|---|---|
| Molecular function | Hydrolase activity, hydrolyzing O-glycosyl compounds | Catalysis of the hydrolysis of any O-glycosyl bond. | ||
| Biological process | Carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. |
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | PREDICTED: probable glucan 1,3-beta-glucosidase A-like isoform X2 [Cicer arietinum] gi|502135628|ref|XP_004502399.1| | 14 | ||
| – | Glucan 1,3-beta-glucosidase [Medicago truncatula] gi|357463267|ref|XP_003601915.1| | 25 | ||
| – | Glucan 1,3-beta-glucosidase; TAIR: AT5G01930.1 Glycosyl hydrolase superfamily protein; Swiss-Prot: sp|B0XN12|EXGA_ASPFC Probable glucan 1,3-beta-glucosidase A; TrEMBL-Plants: tr|K7MPD7|K7MPD7_SOYBN Uncharacterized protein; Found in the gene: LotjaGi6g1v0090200 | 22 | ||
| – | Glucan 1,3-beta-glucosidase; TAIR: AT5G01930.1 Glycosyl hydrolase superfamily protein; Swiss-Prot: sp|B0XN12|EXGA_ASPFC Probable glucan 1,3-beta-glucosidase A; TrEMBL-Plants: tr|V7D1X4|V7D1X4_PHAVU Uncharacterized protein; Found in the gene: LotjaGi6g1v0090200 | 22 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| TRANSMEMBRANE | Phobius | 1 | 25.00 |