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IPR019591 is a Mrp/NBP35 ATP-binding protein.
<p>This entry contains cytosolic Fe-S cluster assembling factors NBP35 and CFD1. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Nucleotide binding and hydrolysis seems to be critical for loading of Fe-S clusters onto CFD1 and NBP35 [[cite:PUB00044419], [cite:PUB00045429], [cite:PUB00045430]]. In higher eukaryotes NBP35 and CFD1 are known as NUBP1 and NUBP2, and NUBP1 is also involved in iron regulation [[cite:PUB00070338]].</p> <p>Bacterial homologues ApbC and MRP (Multiple Resistance and pH adaptation in E. coli) have been shown to contain an ATP-binding domain at the N terminus and have ATPase activity. MRP is a membrane-spanning protein and functions as a Na+/H+ antiporter [[cite:PUB00009818], [cite:PUB00080686]]. Archaeal homologues function as iron-sulfur cluster carriers [[cite:PUB00070336]].</p>
This description is obtained from EB-eye REST.
| Transcript | Name | Description | Predicted domains | Domain count |
|---|---|---|---|---|
| – | Nucleotide binding protein 35 [Theobroma cacao] gi|508719197|gb|EOY11094.1| | 11 | ||
| – | PREDICTED: protein mrp homolog [Glycine max] gi|356531234|ref|XP_003534183.1| | 17 | ||
| – | Nucleotide binding protein 35 [Theobroma cacao] gi|508719197|gb|EOY11094.1| | 14 | ||
| – | PREDICTED: iron-sulfur protein NUBPL-like [Glycine max] gi|356545830|ref|XP_003541337.1| | 10 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|A0A061F9B5|A0A061F9B5_THECC Cytosolic Fe-S cluster assembly factor NBP35; Found in the gene: LotjaGi1g1v0120400 | 14 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|A0A126I632|A0A126I632_PRUPE Cytosolic Fe-S cluster assembly factor NBP35; Found in the gene: LotjaGi1g1v0327200 | 14 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|G7I9X8|G7I9X8_MEDTR Cytosolic Fe-S cluster assembly factor NBP35; Found in the gene: LotjaGi1g1v0448900 | 14 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|G7I9X8|G7I9X8_MEDTR Cytosolic Fe-S cluster assembly factor NBP35; Found in the gene: LotjaGi1g1v0448900 | 14 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|I3SG80|I3SG80_LOTJA Uncharacterized protein; Found in the gene: LotjaGi1g1v0522100_LC | 4 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|A0A126I632|A0A126I632_PRUPE Cytosolic Fe-S cluster assembly factor NBP35; Found in the gene: LotjaGi1g1v0689900 | 14 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT5G50960.1 nucleotide binding protein 35; Swiss-Prot: sp|Q8H1Q2|NBP35_ARATH Cytosolic Fe-S cluster assembly factor NBP35; TrEMBL-Plants: tr|A0A126I632|A0A126I632_PRUPE Cytosolic Fe-S cluster assembly factor NBP35; Found in the gene: LotjaGi1g1v0689900 | 14 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT3G24430.1 ATP binding protein; Swiss-Prot: sp|Q6STH5|HF101_ARATH Fe-S cluster assembly factor HCF101, chloroplastic; TrEMBL-Plants: tr|I1L4F4|I1L4F4_SOYBN Uncharacterized protein; Found in the gene: LotjaGi2g1v0212500 | 21 | ||
| – | Cytosolic Fe-S cluster assembly factor NBP35; TAIR: AT3G24430.1 ATP binding protein; Swiss-Prot: sp|Q6STH5|HF101_ARATH Fe-S cluster assembly factor HCF101, chloroplastic; TrEMBL-Plants: tr|G7KNK7|G7KNK7_MEDTR Nucleotide-binding protein; Found in the gene: LotjaGi2g1v0212500 | 21 |
A list of co-occurring predicted domains within the L. japonicus gene space:
| Predicted domain | Source | Observations | Saturation (%) |
|---|---|---|---|
| cd02037 | CDD | 1 | 7.69 |